Human CD160 Protein, His Tag_天津卡梅德科技发展有限公司

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Human CD160 Protein, His Tag

Human CD160 Protein, His Tag

产品编号

KMP2409

别名

自然杀伤细胞受体BY55, CD160 antigen, CD160

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Catalog Number	KMP2409
Alias	自然杀伤细胞受体BY55, CD160 antigen, CD160
Size	50ug, 100ug, 200ug
Product Description	The Human CD160 Protein(KMP2409) is produced in HEK293 Cells and the target gene encoding Ile27-Ser159 is expressed with a 6His tag at the C-terminus.
Molecular Name	CD160
Product Introduction	CD160：免疫球蛋白超家族（IgSF）糖蛋白，以GPI锚定或跨膜形式表达于NK细胞毒性亚群，通过特异性配体结合参与免疫信号传导。
Molecular Weight	15.62 kDa
Expression System	HEK293 Cells
Species	Human
Purity	>90%
SDS-PAGE
Purification	Affinity Purification
Uniprot ID	O95971
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Formulation	20mM PB, 150mM NaCl, pH7.4
Shipping Condition	In general, the proteins are provided as lyophilized powder which are shipped at ambient temperature. They are shipped out in dry ice if supplied in liquid form.
Background	CD160 antigen is a Lipid-anchor that exists as a disulfide-linked homomultimer. CD160 contains one Ig-like V-type domain. The human CD160 precursor is a cysteine-rich, glycosylphosphatidylinositol-anchored protein of 181 amino acids with a single Ig-like domain. It is weakly homologous to KIR2DL4. CD160 is expressed in the spleen, peripheral blood, and small intestine. Its expression is tightly associated with peripheral blood NK cells and CD8 T lymphocytes with cytolytic effector activity. CD160 is a receptor showing broad specificity for both classical and non-classical MHC class I molecules.
Endotoxin	<1.0 EU/ug determined by the LAL method
Product Declaration	该产品仅供科研使用，不可直接用于人体或注射。

FAQ

蛋白溶解后浓度偏低，如何调整？

低速离心：12,000 rpm, 5分钟，去除不溶物。缓冲液置换：使用超滤离心管（如10 kDa截留分子量）浓缩。
如何提高重组蛋白的可溶性表达？

可优化表达条件（如降低诱导温度、调整IPTG浓度）、使用促溶标签（如SUMO、GST）、共表达分子伴侣，或尝试不同宿主系统（如哺乳动物细胞或昆虫细胞）以提高可溶性蛋白产量。

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