KRP511
白细胞介素-31受体亚单位alpha, Interleukin-31 receptor subunit alpha , IL-31 receptor subunit alpha, IL-31R subunit alpha, IL-31R-alpha, IL-31RA, GLM-R, mGLM-R, Gp130-like monocyte receptor, Gp130-like receptor, Novel cytokine receptor 10, NR10, ZcytoR17, Glmr, Inte
| Catalog Number | KRP511 |
| Alias | 白细胞介素-31受体亚单位alpha, Interleukin-31 receptor subunit alpha , IL-31 receptor subunit alpha, IL-31R subunit alpha, IL-31R-alpha, IL-31RA, GLM-R, mGLM-R, Gp130-like monocyte receptor, Gp130-like receptor, Novel cytokine receptor 10, NR10, ZcytoR17, Glmr, Inte |
| Size | 20ug, 50ug, 100ug, 200ug, 1mg |
| Product Description | Mouse Il31ra(Val19-Ser503) |
| Molecular Name | Il31ra |
| Product Introduction | 白细胞介素-31受体亚单位alpha通过对免疫球蛋白样受体的调节，影响免疫系统的功能。。 |
| Molecular Weight | 90-103 kDa |
| Expression System | HEK293F Cells |
| Species | Mouse |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purity | ≥95% |
| SDS-PAGE | |
| Purification | Affinity Purification |
| Uniprot ID | Q8K5B1-1 |
| Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. |
| Formulation | Supplied in PBS |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Background | Associates with OSMR to form the interleukin-31 receptor which activates STAT3 and to a lower extent STAT1 and STAT5. May function in skin immunity (PubMed:15184896). Mediates IL31-induced itch, probably in a manner dependent on cation channels TRPA1 and TRPV1 (PubMed:24373353). Positively regulates numbers and cycling status of immature subsets of myeloid progenitor cells in bone marrow in vivo and enhances myeloid progenitor cell survival in vitro (PubMed:17379091). {ECO:0000269|PubMed:15184896, ECO:0000269|PubMed:17379091, ECO:0000269|PubMed:24373353}. |
| Endotoxin | < 0.1 EU per ug |
| Biological Activity | Measured by its binding ability in a functional ELISA. When Recombinant Mouse IL‑31 RA Fc Chimera is immobilized at 5 µg/mL (100 µL/well), Recombinant Mouse IL‑31 binds with an ED50 of 0.9-5.4 μg/mL. |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
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