Mouse CD276 Protein, His Tag_天津卡梅德科技发展有限公司

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Mouse CD276 Protein, His Tag

Mouse CD276 Protein, His Tag

产品编号

KMP2348

别名

共刺激分子蛋白, CD276 antigen, CD276, B7 homolog 3

规格

50ug
100ug
200ug

DATASHEET MSDS

立即询价加入询价列表大包装定制

产品介绍

Catalog Number	KMP2348
Alias	共刺激分子蛋白, CD276 antigen, CD276, B7 homolog 3
Size	50ug, 100ug, 200ug
Product Description	The Mouse CD276 Protein(KMP2348) is produced in HEK293 Cells and the target gene encoding Val29-Phe244 is expressed with a 6His tag at the C-terminus.
Molecular Name	CD276
Product Introduction	CD276（B7-H3）：免疫球蛋白超家族（IgSF）成员，通过跨膜形式参与免疫细胞活化和功能调节。
Molecular Weight	24.32 kDa
Expression System	HEK293 Cells
Species	Mouse
Purity	>95%
SDS-PAGE
Purification	Affinity Purification
Uniprot ID	Q8VE98
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Formulation	PBS, pH7.4
Shipping Condition	In general, the proteins are provided as lyophilized powder which are shipped at ambient temperature. They are shipped out in dry ice if supplied in liquid form.
Background	CD276, also known as B7-H3, is a member of the B7 superfamily with signature IgV and IgG regions in extracellular domains. It is a type I transmembrane protein and shares 20–27% amino acid identity with other B7 family members. B7-H3 is involved in the activation of T lymphocytes, and regulates murine bone formation. It is also reported that B7-H3 may play an important role in muscle-immune interactions, providing further evidence of the active role of muscle cells in local immunoregulatory processes. B7-H3 is expressed on T-cells, natural killer cells, and antigen presenting cells, as well as some non-immune cells, such as osteoblasts, fibroblasts, fibroblast-like synoviocytes and epithelial cells. High expression of B7-H3 in tumor vasculature also correlates with poor survival in patients, suggesting that it may play a role in tumor cell migration.
Endotoxin	<1.0 EU/ug determined by the LAL method
Product Declaration	该产品仅供科研使用，不可直接用于人体或注射。

FAQ

如何储存293F细胞中表达的蛋白？

蛋白可以在-80°C下储存以便长期保存。应分装并避免冻融循环，以保持蛋白的稳定性。
如何提高293F细胞中的蛋白表达效率？

可以通过优化质粒设计、使用高效转染试剂、优化细胞培养条件以及使用蛋白折叠伴侣或密码子优化来提高蛋白表达效率。

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