Recombinant Human EGFR Protein, His tag
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产品编号
KMPH7115
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别名
表皮生长因子受体;Epidermal growth factor receptor; EGFR; ERBB; ERBB1; HER1
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规格
- 100ug
| Catalog Number | KMPH7115 |
| Alias | 表皮生长因子受体;Epidermal growth factor receptor; EGFR; ERBB; ERBB1; HER1 |
| Size | 100ug |
| Product Description | The Recombinant Human EGFR Protein with His Tag (KMPH7115) is expressed from E.coli. It contains 1071-1150 AA. |
| Molecular Name | EGFR |
| Expression System | E.coli |
| Species | Human |
| Concentration | Batch to Batch |
| Purity | > 90% as determined by SDS-PAGE |
| Purification | Affinity Purification |
| Storage Condition | Store at -80°C. Avoid repeated freeze-thaw cycles. |
| Formulation | 0.01 M PBS, pH 7.2-7.4 |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Background | As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR protein plays a crucial role in signaling pathway in the regulation of cell proliferation, survival and differentiation. Binding of a ligand induces EGFR protein homo- or heterodimerization, the subsequent tyrosine autophosphorylation and initiates various down stream pathways (MAPK, PI3K/PKB and STAT). In addition, EGFR signaling also has been shown to exert action on carcinogenesis and disease progression, and thus EGFR protein is proposed as a target for cancer therapy currently. |
| Predicted Molecular Weight | 11 kDa |
| Tag | C-His Tag |
| Product Declaration | 该产品仅供科研使用,不可直接用于人体或注射。 |
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