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Recombinant Human RAGE/AGER Protein, His tag

Recombinant Human RAGE/AGER Protein, His tag

产品编号

KMPH11256

别名

晚期糖基化终末产物受体;Receptor for advanced glycosylation end products; Advanced glycosylation end product-specific receptor; AGER; RAGE

规格
  • 100ug
产品介绍
Catalog NumberKMPH11256
Alias晚期糖基化终末产物受体;Receptor for advanced glycosylation end products; Advanced glycosylation end product-specific receptor; AGER; RAGE
Size100ug
Product DescriptionThe Recombinant Human RAGE/AGER Protein with His Tag (KMPH11256) is expressed from E.coli. It contains 91-274 AA.
Molecular NameRAGE/AGER
Expression SystemE.coli
SpeciesHuman
HostE.coli
ConcentrationBatch to Batch
Purity> 90% as determined by SDS-PAGE
PurificationAffinity Purification
Storage ConditionStore at -80°C. Avoid repeated freeze-thaw cycles.
FormulationLyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Shipping ConditionThis product is shipped on ice packs or dry ice.
BackgroundThe Advanced Glycosylation End product-specific Receptor (AGER, commonly known as RAGE) is a pattern recognition receptor belonging to the immunoglobulin superfamily that binds advanced glycation end products (AGEs). It is expressed in endothelial cells, monocytes, neurons, and smooth muscle, and is highly abundant during development before declining in adulthood. Elevated AGER expression is implicated in diabetic complications—including vasculopathy, neuropathy, and retinopathy—as well as Alzheimer’s disease, where it interacts with amyloid-beta to promote oxidative stress and cellular dysfunction.
Predicted Molecular Weight22.36 kDa
TagN-His Tag
ReconstitutionReconstitute in sterile water for a stock solution.
Product Declaration该产品仅供科研使用,不可直接用于人体或注射。

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