Recombinant Human AIM2 Protein, His tag_天津卡梅德科技发展有限公司

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Recombinant Human AIM2 Protein, His tag

Recombinant Human AIM2 Protein, His tag

产品编号

KMP5203

别名

黑色素瘤缺失蛋白 2；Absent in melanoma 2; Interferon-inducible protein AIM2; AIM2

规格

100ug

DATASHEET MSDS

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产品介绍

Catalog Number	KMP5203
Alias	黑色素瘤缺失蛋白 2；Absent in melanoma 2; Interferon-inducible protein AIM2; AIM2
Size	100ug
Product Description	The Recombinant Human AIM2 Protein with His Tag (KMP5203) is expressed from E.coli. It contains 1-342 AA.
Molecular Name	AIM2
Expression System	E.coli
Species	Human
Concentration	Batch to Batch
Purity	> 90% as determined by SDS-PAGE
Purification	Affinity Purification
Storage Condition	Store at -80°C. Avoid repeated freeze-thaw cycles.
Formulation	Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Shipping Condition	This product is shipped on ice packs or dry ice.
Background	As a member of the interferon-inducible protein family IFI20X/IFI16, AIM2 is a cytoplasmic protein that contributes to innate immune responses and is implicated in tumorigenic reversion and the regulation of cell proliferation. Interferon-gamma induces the expression of AIM2, which upon activation can form an inflammasome complex by recruiting ASC and caspase-1, leading to IL-1β and IL-18 maturation. This pathway underscores its role in inflammation and antitumor immunity. Furthermore, aberrant AIM2 expression has been associated with various cancers, suggesting its potential as a biomarker or therapeutic target in oncology.
Predicted Molecular Weight	41.16 kDa
Tag	N-His Tag
Reconstitution	Reconstitute in sterile water for a stock solution.
Product Declaration	该产品仅供科研使用，不可直接用于人体或注射。

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