Inactivated Pneumococcal Type 14 Antigen_天津卡梅德科技发展有限公司

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Inactivated Pneumococcal Type 14 Antigen

Inactivated Pneumococcal Type 14 Antigen

产品编号

BAG1120

别名

灭活14型肺炎球菌抗原,灭活肺炎球菌抗原, 肺炎球菌, Inactivated Pneumococcal Type 14, Pneumococcal

规格

250ul
1ml

DATASHEET MSDS

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产品介绍

Catalog Number	BAG1120
Alias	灭活14型肺炎球菌抗原,灭活肺炎球菌抗原, 肺炎球菌, Inactivated Pneumococcal Type 14, Pneumococcal
Size	250ul, 1ml
Molecular Name	Pneumococcal
Expression System	Pneumococcal
Species	Bacteria
Purity	>95%
Purification	IEC & HPLC
Storage Condition	Store the lyophilized powder at 4℃ for 6 months. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles.
Formulation	Powder or 0.1M PBS, PH 7.0
Background	The symptoms of pneumococcal pneumonia can occur suddenly, typically presenting as a severe chill, later including a severe fever, cough, shortness of breath, rapid breathing, and chest pains. Other symptoms like nausea, vomiting, headache, fatigue, and muscle aches could also accompany the original symptoms. Sometimes the coughing can produce rusty or blood-streaked sputum. In 25% of cases, a parapneumonic effusion may occur. Chest X-rays will typically show lobar consolidation or patchy infiltrates.
Application	Immunogen, WB, ELISA

FAQ

CRM197是什么？它在肺炎球菌疫苗中扮演什么角色？

CRM197 是一种无毒的白喉毒素突变体蛋白。它本身没有毒性，但保留了极强的免疫原性。在肺炎球菌结合疫苗中，它的角色是 “蛋白质载体” 。核心作用：肺炎球菌的荚膜多糖（针对不同血清型，如4型、6B型、19F型等）属于T细胞非依赖性抗原。单独接种时，它们在婴幼儿体内只能引起较弱的免疫反应，且不能产生免疫记忆。通过化学方法将这些多糖共价结合到CRM197载体蛋白上，就将疫苗变成了 “T细胞依赖性抗原” 。这使得婴幼儿的免疫系统能够被有效激活，产生更强、更持久的保护性抗体，并形成免疫记忆。

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