Inactivated Pneumococcal Type 17F Antigen_天津卡梅德科技发展有限公司

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Inactivated Pneumococcal Type 17F Antigen

Inactivated Pneumococcal Type 17F Antigen

产品编号

BAG1122

别名

灭活17F型肺炎球菌抗原,灭活肺炎球菌抗原, 肺炎球菌, Inactivated Pneumococcal Type 17F, Pneumococcal

规格

250ul
1ml

DATASHEET MSDS

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产品介绍

Catalog Number	BAG1122
Alias	灭活17F型肺炎球菌抗原,灭活肺炎球菌抗原, 肺炎球菌, Inactivated Pneumococcal Type 17F, Pneumococcal
Size	250ul, 1ml
Molecular Name	Pneumococcal
Product Introduction	Pneumococcal: 肺炎球菌（的），指与肺炎链球菌相关的，如其疫苗、疾病或成分。
Expression System	Pneumococcal
Species	Bacteria
Purity	>95%
Purification	IEC & HPLC
Storage Condition	Store the lyophilized powder at 4℃ for 6 months. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles.
Formulation	Powder or 0.1M PBS, PH 7.0
Background	Pneumococcal pneumonia is a type of bacterial pneumonia that is caused by Streptococcus pneumoniae (which is also called pneumococcus). It is the most common bacterial pneumonia found in adults, the most common type of community-acquired pneumonia, and one of the common types of pneumococcal infection. The estimated number of Americans with pneumococcal pneumonia is 900, 000 annually, with almost 400, 000 cases hospitalized and fatalities accounting for 5-7% of these cases.
Application	Immunogen, WB, ELISA

FAQ

CRM197结合型抗原的制备流程是怎样的？

这是一个高度复杂和精密的生物化学过程，主要步骤包括： CRM197蛋白生产：通过基因工程菌（如Corynebacterium diphtheriae 或重组E. coli）发酵生产，并经过多步纯化得到高纯度CRM197蛋白。多糖活化：对特定血清型的肺炎球菌荚膜多糖进行化学修饰（例如，使用氰化溴、CDAP或高碘酸钠等），在其链上引入活性基团（如氰酸酯、醛基）。连接（结合）：将活化的多糖与CRM197蛋白上的氨基（通常是赖氨酸残基的ε-氨基）在控制条件下进行化学反应，形成稳定的共价键。纯化与鉴定：对结合产物进行纯化，去除未反应的多糖和蛋白，并通过多种分析技术（如SEC-HPLC、SDS-PAGE、免疫学方法等）确定结合率、分子大小、游离多糖含量等关键质量属性。

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