| Catalog Number | KRP584 |
| Alias | 肿瘤坏死因子受体超家族成员27, Tumor necrosis factor receptor superfamily member 27 , X-linked ectodysplasin-A2 receptor, EDA-A2 receptor, TNFRSF27, XEDAR, UNQ2448/PRO5727/PRO34080, |
| Size | 20ug, 50ug, 100ug, 200ug, 1mg |
| Product Description | Human EDA2R(1-136 aa) |
| Molecular Name | EDA2R |
| Product Introduction | 肿瘤坏死因子受体超家族成员27参与调节免疫反应与细胞凋亡，影响癌症的发生与发展。。 |
| Molecular Weight | 26-30 kDa |
| Expression System | HEK293F Cells |
| Species | Human |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purity | ≥95% |
| SDS-PAGE |  |
| Purification | Affinity Purification |
| Uniprot ID | Q9HAV5 |
| Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. |
| Formulation | Supplied in PBS |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Background | Receptor for EDA isoform A2, but not for EDA isoform A1. Mediates the activation of the NF-kappa-B and JNK pathways. Activation seems to be mediated by binding to TRAF3 and TRAF6. {ECO:0000269|PubMed:12270937}. |
| Endotoxin | < 0.1 EU per ug |
| Biological Activity | Measured by its binding ability in a functional ELISA. When Recombinant Human EDAA2/Ectodysplasin A2 is immobilized at 1 µg/mL (100 µL/well), Recombinant Human EDA2R/TNFRSF27/XEDAR His-tag binds with an ED50 of 40.0-500 ng/mL. |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
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