| Catalog Number | KRP573 |
| Alias | 白细胞介素-1受体样2, Interleukin-1 receptor-like 2 , EC 3.2.2.6, IL-36 receptor, Interleukin-1 receptor-related protein 2, IL-1Rrp2, IL1R-rp2, |
| Size | 20ug, 50ug, 100ug, 200ug, 1mg |
| Product Description | Mouse Il1rl2(22-338 aa (A158V)) |
| Molecular Name | Il1rl2 |
| Product Introduction | 白细胞介素-1受体样2通过介导免疫系统反应，影响炎症过程。。 |
| Molecular Weight | 55-68 kDa |
| Expression System | HEK293F Cells |
| Species | Mouse |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purity | ≥90% |
| SDS-PAGE | |
| Purification | Affinity Purification |
| Uniprot ID | Q9ERS7 |
| Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. |
| Formulation | Supplied in PBS |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Background | Receptor for interleukin-36 (IL36A, IL36B and IL36G). After binding to interleukin-36 associates with the coreceptor IL1RAP to form the interleukin-36 receptor complex which mediates interleukin-36-dependent activation of NF-kappa-B, MAPK and other pathways. The IL-36 signaling system is thought to be present in epithelial barriers and to take part in local inflammatory response; it is similar to the IL-1 system. Seems to be involved in skin inflammatory response by induction of the IL-23/IL-17/IL-22 pathway. {ECO:0000269|PubMed:21860022, ECO:0000269|PubMed:23064362}. |
| Endotoxin | < 0.1 EU per ug |
| Biological Activity | Measured by its binding ability in a functional ELISA. Immobilized rmIL- 1F5,rmIL-1F6, or rmIL-1F8 at 1 µg/mL (100 µL/well) can bind rmIL-1 Rrp2/his with a linearrange of 0.078-5 µg/mL. |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
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