| Catalog Number | KRP159 |
| Alias | 组织因子途径抑制剂, Tissue factor pathway inhibitor , TFPI, Extrinsic pathway inhibitor, EPI, Lipoprotein-associated coagulation inhibitor, LACI, LACI, TFPI1, |
| Size | 20ug, 50ug, 100ug, 200ug, 1mg |
| Product Description | Human TFPI(Asp29-Lys282) |
| Molecular Name | TFPI |
| Product Introduction | 组织因子途径抑制剂通过抑制外源性途径,调节凝血和免疫反应。。 |
| Molecular Weight | 37-50 kDa |
| Expression System | HEK293F Cells |
| Species | Human |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purity | ≥95% |
| SDS-PAGE |  |
| Purification | Affinity Purification |
| Uniprot ID | P10646 |
| Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. |
| Formulation | Supplied in PBS |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Background | Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma. {ECO:0000269|PubMed:20676107}. |
| Endotoxin | < 0.1 EU per ug |
| Biological Activity | Measured by its ability to inhibit trypsin cleavage of a fluorogenic peptide substrate, Mca-RPKPVE-Nval-WRK(Dnp)-NH2. The IC50 value is <0.41 nM. |
| Product Declaration | 该产品仅供科研使用,不可直接用于人体或注射。 |