| Catalog Number | KRP154 |
| Alias | 溶酶体α-葡萄糖苷酶, Lysosomal alpha-glucosidase , EC 3.2.1.20, Acid maltase, Aglucosidase alfa, [Cleaved into: 76 kDa lysosomal alpha-glucosidase; 70 kDa lysosomal alpha-glucosidase], |
| Size | 20ug, 50ug, 100ug, 200ug, 1mg |
| Product Description | Human GAA(70-952 aa) |
| Molecular Name | GAA |
| Product Introduction | 溶酶体α-葡萄糖苷酶参与糖代谢的酶,缺乏时会导致糖原累积病。。 |
| Molecular Weight | 95-105 kDa |
| Expression System | HEK293F Cells |
| Species | Human |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purity | ≥95% |
| SDS-PAGE |  |
| Purification | Affinity Purification |
| Uniprot ID | P10253 |
| Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. |
| Formulation | Supplied in PBS |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Background | Essential for the degradation of glycogen in lysosomes (PubMed:14695532, PubMed:18429042, PubMed:1856189, PubMed:7717400). Has highest activity on alpha-1,4-linked glycosidic linkages, but can also hydrolyze alpha-1,6-linked glucans (PubMed:29061980). {ECO:0000269|PubMed:14695532, ECO:0000269|PubMed:18429042, ECO:0000269|PubMed:1856189, ECO:0000269|PubMed:29061980, ECO:0000269|PubMed:7717400}. |
| Endotoxin | < 0.1 EU per ug |
| Biological Activity | Measured by its ability to release glucose from starch. The specific activity is >7,500 pmol/min/μg, as measured under the described conditions. |
| Product Declaration | 该产品仅供科研使用,不可直接用于人体或注射。 |