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Recombinant Mouse IL-7 Protein, No tag

Recombinant Mouse IL-7 Protein, No tag

产品编号

KRP153

别名

白细胞介素-7(IL-7), Interleukin-7 , IL-7, Il-7,

规格
  • 20ug
  • 50ug
  • 100ug
  • 200ug
  • 1mg
产品介绍
Alias白细胞介素-7(IL-7), Interleukin-7 , IL-7, Il-7,
Catalog NumberKRP153
Molecular NameIl7
Molecular Weight18 kDa
Size20ug, 50ug, 100ug, 200ug, 1mg
Concentration联系销售经理获得最新批次的浓度
Purity≥95%
Product DescriptionMouse Il7(26-154 aa)
Storage ConditionStore the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles.
Formulation<1.0EU/ug
Shipping ConditionThis product is shipped on ice packs or dry ice.
BackgroundHematopoietic cytokine that plays an essential role in the development, expansion, and survival of naive and memory T-cells and B-cells thereby regulating the number of mature lymphocytes and maintaining lymphoid homeostasis (PubMed:28811625, PubMed:7699333). Mechanistically, exerts its biological effects through a receptor composed of IL7RA subunit and the cytokine receptor common subunit gamma/CSF2RG. Binding to the receptor leads to activation of various kinases including JAK1 or JAK3 depending on the cell type and subsequently propagation of signals through activation of several downstream signaling pathways including the PI3K/Akt/mTOR or the JAK-STAT5. {ECO:0000250|UniProtKB:P13232, ECO:0000269|PubMed:28811625, ECO:0000269|PubMed:7699333}.
SpeciesMouse
PurificationAffinity Purification
EndotoxinSupplied in PBS
Biological ActivityMeasured in a cell proliferation assay using antibody against CD3- activated human peripheral blood mononuclear cell (PBMC). The ED50 forthis effect is typically 0.4-4 ng/mL.
Uniprot IDP10168
Product Declaration该产品仅供科研使用,不可直接用于人体或注射。
Display PeptidesE. coli

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