Recombinant Mouse IL-7 Protein, No tag
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产品编号
KRP153
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别名
白细胞介素-7（IL-7）, Interleukin-7 , IL-7, Il-7,
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规格
- 20ug
- 50ug
- 100ug
- 200ug
- 1mg
产品介绍
| Catalog Number | KRP153 |
| Alias | 白细胞介素-7（IL-7）, Interleukin-7 , IL-7, Il-7, |
| Size | 20ug, 50ug, 100ug, 200ug, 1mg |
| Product Description | Mouse Il7(26-154 aa) |
| Molecular Name | Il7 |
| Product Introduction | 白细胞介素-7（IL-7）调节B细胞生长和分化的细胞因子。。 |
| Molecular Weight | 18 kDa |
| Expression System | E. coli |
| Species | Mouse |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purity | ≥95% |
| Purification | Affinity Purification |
| Uniprot ID | P10168 |
| Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. |
| Formulation | Supplied in PBS |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Background | Hematopoietic cytokine that plays an essential role in the development, expansion, and survival of naive and memory T-cells and B-cells thereby regulating the number of mature lymphocytes and maintaining lymphoid homeostasis (PubMed:28811625, PubMed:7699333). Mechanistically, exerts its biological effects through a receptor composed of IL7RA subunit and the cytokine receptor common subunit gamma/CSF2RG. Binding to the receptor leads to activation of various kinases including JAK1 or JAK3 depending on the cell type and subsequently propagation of signals through activation of several downstream signaling pathways including the PI3K/Akt/mTOR or the JAK-STAT5. {ECO:0000250|UniProtKB:P13232, ECO:0000269|PubMed:28811625, ECO:0000269|PubMed:7699333}. |
| Endotoxin | ＜1.0EU/ug |
| Biological Activity | Measured in a cell proliferation assay using antibody against CD3- activated human peripheral blood mononuclear cell (PBMC). The ED50 forthis effect is typically 0.4-4 ng/mL. |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
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