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Rabbit Anti-RGS19 Polyclonal Antibody
Rabbit Anti-RGS19 Polyclonal Antibody

Rabbit Anti-RGS19 Polyclonal Antibody

产品编号

PAV3351

别名

regulator of G protein signaling 19, GAIP, RGSGAIP

目录价格

InquiryRMB

规格
  • 100ul
产品介绍
Aliasregulator of G protein signaling 19, GAIP, RGSGAIP
Catalog NumberPAV3351
Product DescriptionRabbit polyclonal antibody raised against human RGS19 (Regulator of G protein signaling 19). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml.
Molecular NameRGS19
SpeciesHuman, Mouse, Rat
HostRabbit
Size100ul
ClonityPolyclonal
Protein Family小G蛋白与适配蛋白
Concentration1 mg/ml
Purificationaffinity-chromatography
Formulationsupply in PBS containing 50% glycerol, and 0.02% sodium azide.
BackgroundG proteins mediate a number of cellular processes. The protein encoded by this gene belongs to the RGS (regulators of G-protein signaling) family and specifically interacts with G protein, GAI3. This protein is a guanosine triphosphatase-activating protein that functions to down-regulate Galpha i/Galpha q-linked signaling. Alternatively spliced transcript variants encoding the same protein isoform have been found for this gene. [provided by RefSeq, Jul 2008]
ImmunogenThis antibody was raised against from part region of human RGS19 protein (UniProt: P49795)
ApplicationWB, ELISA
Recommended DilutionWB 1:500-2000 ELISA 1:5000-20000
Gene ID10287
TagUnconjugated
Cross-reactivityHuman, Mouse, Rat
Predicted Molecular Weight≈24.6 kDa
Storage ConditionStore at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles.
Shipping ConditionThis product is shipped on blue ice.
Molecular Weight24.6 kDa
Cross-reactivityHuman, Mouse, Rat
Uniprot IDP49795
NoteGene ID: 10287; UniProt: P49795; Chromosome: 20q13.33; Predicted MW: 24.6 kDa
FunctionInhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G-alpha subfamily 1 members, with the order G(i)a3 > G(i)a1 > G(o)a >> G(z)a/G(i)a2. Activity on G(z)-alpha is inhibited by phosphorylation and palmitoylation of the G protein.
Product Declaration本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。
Product Full NameRabbit Anti-Human RGS19 Polyclonal Antibody
TargetRGS19

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