Rabbit Anti-MBIP1/MBIP Polyclonal Antibody
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产品编号
PAV2255
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别名
MAP3K12 binding inhibitory protein 1
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | MAP3K12 binding inhibitory protein 1 |
| Catalog Number | PAV2255 |
| Product Description | Rabbit polyclonal antibody raised against human MBIP (MAP3K12-binding inhibitory protein 1). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | MBIP |
| Species | Human |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 细胞周期 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | Enables identical protein binding activity and protein kinase inhibitor activity. Involved in several processes, including positive regulation of JNK cascade; regulation of gene expression; and regulation of tubulin deacetylation. Located in cytosol; nucleolus; and nucleoplasm. Part of ATAC complex. [provided by Alliance of Genome Resources, Jun 2026] |
| Immunogen | This antibody was raised against from part region of human MBIP protein (UniProt: Q9NS73) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 51562 |
| Tag | Unconjugated |
| Cross-reactivity | Human |
| Predicted Molecular Weight | ≈39.3 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 39.3 kDa |
| Cross-reactivity | Human |
| Uniprot ID | Q9NS73 |
| Note | Gene ID: 51562; UniProt: Q9NS73; Chromosome: 14q13.3; Predicted MW: 39.3 kDa |
| Function | Functions as part of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. Inhibits the MAP3K12 activity to induce the activation of the JNK/SAPK pathway. Together with MOCS2B, inhibits the activity of stress kinase EIF2AK2/PKR; this may lead to effects such as suppression of JNK activation and subsequent stress-responsive transcription, or suppression of eIF2a phosphorylation to favor translation. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human MBIP Polyclonal Antibody |
| Target | MBIP |
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