Rat TL1A Protein, hFc Tag

产品编号

KMP4204

别名

TNF配体相关分子1A, TL1A Protein, Rat TL1A Protein, hFc Tag

规格

50ug
100ug
200ug

DATASHEET COA

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产品介绍

Alias	TNF配体相关分子1A, TL1A Protein, Rat TL1A Protein, hFc Tag
Catalog Number	KMP4204
Product Description	The Rat TL1A Protein(KMP4204) is produced in HEK293 Cells. A DNA sequence encoding the rat TNFSF15 (Q8K3Y7) (Asp94-Ile252) is expressed, fused with the Fc region of human IgG1 at the N-terminus.
Molecular Name	TL1A
Species	Rat
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>90% as determined by SDS-PAGE
Concentration	联系销售经理获得最新批次的浓度
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	TL1A, also known as TNFSF15, is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. It is specifically expressed in endothelial cells. TL1A also can be detected in monocytes, placenta, lung, liver, kidney, skeletal muscle, pancreas, spleen, prostate, small intestine and colon. TL1A is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It mediates activation of NF-kappa-B. It also inhibits vascular endothelial growth and angiogenesis (in vitro). TL1A promotes activation of caspases and apoptosis. It is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor.
Cross-reactivity	No cross-reactivity with other antigens or proteins.
Predicted N Terminus	Asp 94
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	46.5 kDa
Product Declaration	该产品仅供科研使用，不可直接用于人体或注射。
Temperature Range	Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -25℃. Avoid repeated freeze-thaw cycles.