| Alias | FCGRT和B2M异二聚体蛋白, Human FCGRT & B2M Heterodimer Protein, His Tag, Avi Tag, FCGRT & B2M Heterodimer |
| Catalog Number | KMP3551 |
| Product Description | The Human FCGRT & B2M Heterodimer Protein(KMP3551) is produced in HEK293 Cells. The target gene encoding the extracellular domain (Met1-Ser297) of human FCGRT (NP_004098.1) is fused with a C-terminal polyhistidine tagged Avi tag at the C-terminus, constructed the plasmid 1; The target gene encoding the human B2M (NP_004039.1) (Met1-Met119) constructed the plasmid 2. The two plasmids are co-expressed and the human FCGRT/B2M heterodimer is purified. The purified heterodimer is biotinylated in vivo by the Biotin-Protein ligase (BirA enzyme) which is co-expressed. |
| Molecular Name | FCGRT & B2M Heterodimer |
| Species | Human |
| Host | HEK293 Cells |
| Size | 50ug, 100ug, 200ug |
| Protein Family | Other protein |
| Purity | >95% as determined by SDS-PAGE |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purification | Affinity purification |
| Endotoxin | <1.0 EU/ug determined by the LAL method |
| Formulation | PBS, pH7.4 |
| Background | FCGRT (Fc Gamma Receptor And Transporter) is a Protein Coding gene. Diseases associated with FCGRT include Immunodeficiency 43 and Immunoglobulin G Deficiency. Gene Ontology (GO) annotations related to this gene include antigen binding and beta-2-microglobulin binding. An important paralog of this gene is HLA-F. B2M (Beta-2-Microglobulin) is a Protein Coding gene. Diseases associated with B2M include Immunodeficiency 43 and Amyloidosis, Familial Visceral. Among its related pathways are SARS-CoV-2 Infection and Infectious disease. Gene Ontology (GO) annotations related to this gene include identical protein binding. An important paralog of this gene is HLA-DPA1. |
| Application | WB, ELISA |
| Recommended Dilution | ELISA: 1:100-1:1000 |
| Cross-reactivity | No cross-reactivity with other antigens or proteins. |
| Predicted Molecular Weight | 45.3 kDa |
| Predicted N Terminus | Met |
| Reconstitution | Not applicable. The product is supplied as a ready-to-use liquid formulation. |
| Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
| Remarks | 收到产品后请立即按保存条件储存；使用前短暂离心，使内容物集中于管底；避免反复冻融。 |
| Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
| Stability | Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
| Molecular Weight | 45.3 kDa |
| Cross-reactivity | No cross-reactivity with other antigens or proteins. |
| Note | 仅供科研使用 |
| ELISA IC50(ppb) | ≥ 1:1000 |
| Function | FCGRT (Fc Gamma Receptor And Transporter) is a Protein Coding gene. Diseases associated with FCGRT include Immunodeficiency 43 and Immunoglobulin G Deficiency. Gene Ontology (GO) annotations related to this gene include antigen binding and beta-2-microglobulin binding. An important paralog of this gene is HLA-F. B2M (Beta-2-Microglobulin) is a Protein Coding gene. Diseases associated with B2M include Immunodeficiency 43 and Amyloidosis, Familial Visceral. Among its related pathways are SARS-CoV-2 Infection and Infectious disease. Gene Ontology (GO) annotations related to this gene include identical protein binding. An important paralog of this gene is HLA-DPA1. |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
| Temperature Range | -20℃ ~ -80℃ |
| Solubility | 产品为即用型液体，无需复溶。 |
| Appearance | Liquid |
| Product Full Name | Human FCGRT & B2M Heterodimer Protein, His Tag |
| Preservative Solution | PBS, pH7.4 |
| Usage Method | 冻干粉请按“复溶”说明用无菌去离子水复溶后使用，液体产品可直接使用；具体工作浓度请参考“推荐稀释比例”。 |
| Target | FCGRT & B2M Heterodimer |
销售微信
官方公众号
0
