Rabbit Anti-SUN5 Polyclonal Antibody
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产品编号
PAV3877
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别名
Sad1 and UNC84 domain containing 5, SPAG4L, SPGF16, TSARG4, dJ726C3.1
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | Sad1 and UNC84 domain containing 5, SPAG4L, SPGF16, TSARG4, dJ726C3.1 |
| Catalog Number | PAV3877 |
| Product Description | Rabbit polyclonal antibody raised against human SUN5 (SUN domain-containing protein 5). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | SUN5 |
| Species | Human |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 细胞骨架 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | The protein encoded by this gene appears to play a role in the meiotic stage of spermatogenesis. The encoded protein localizes to the junction between the sperm head and body and may be involved in nuclear envelope reconstitution and nuclear migration. Mutations in this gene have been implicated in acephalic spermatozoa syndrome. [provided by RefSeq, May 2017] |
| Immunogen | This antibody was raised against from part region of human SUN5 protein (UniProt: Q8TC36) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 140732 |
| Tag | Unconjugated |
| Cross-reactivity | Human |
| Predicted Molecular Weight | ≈43.1 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 43.1 kDa |
| Cross-reactivity | Human |
| Uniprot ID | Q8TC36 |
| Note | Gene ID: 140732; UniProt: Q8TC36; Chromosome: 20q11.21; Predicted MW: 43.1 kDa |
| Function | Required for male fertility. Plays an essential role in maintenance of sperm head-to-tail attachment during late stages of spermiogenesis, via promoting secure attachment of the nuclear envelope to the flagellum coupling apparatus (Probable). Component of the LMNB1/SUN5/SEPT12 bridge that connects the sperm proximal centriole to the implantation fossa, the bridge functions to prevent detachment of the proximal centriole from the posterior nucleus during spermiogenesis. Required for localization of SEPT12 at the implantation fossa of sperm cells during spermiogenesis (By similarity). |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human SUN5 Polyclonal Antibody |
| Target | SUN5 |
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