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Recombinant Human HEPACAM Protein, His Tag

Recombinant Human HEPACAM Protein, His Tag

Recombinant Human HEPACAM Protein, His Tag

产品编号

KMH1208

别名

HEPN1, MLC2A, MLC2B, GlialCAM, hepatic and glial cell adhesion molecule

规格

50ug
100ug

DATASHEET COA

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产品介绍

Alias	HEPN1, MLC2A, MLC2B, GlialCAM, hepatic and glial cell adhesion molecule
Catalog Number	KMH1208
Molecular Name	HEPACAM
Species	Human
Host	Mammalian cells
Size	50ug, 100ug
Protein Family	Other protein
Purity	≥90% as determined by SDS-PAGE
Purification	Affinity Purification
Endotoxin	< 1.0 EU per ug of the protein as determined by the LAL method.
Formulation	PBS
Background	Hepatocyte Cell Adhesion Molecule (HEPACAM) is a single-pass type I membrane protein that localizes to the cytoplasmic side of the cell membrane. HEPACAM includes a signal sequence (amino acid 1-33), an extracellular region (amino acid 34-24) with one Ig-like C2-type domain and one Ig-like V-type domain, a transmembrane segment (amino acid 241-261), and a cytoplasmic domain (amino acid 262 - 416). The cytoplasmic domain plays an important role in regulation of cell-matrix adhesion and cell motility. HEPACAM acts as a homodimer and dimer formation occurs predominantly through cis interactions on the cell surface. HEPACAM is involved in cell motility and cell-matrix interactions. The expression of this gene is down-regulated or undetectable in many cancer cell lines, so this may be a tumor suppressor gene.
Storage Condition	Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping Condition	This product is shipped on ice packs or dry ice.
Molecular Weight	22.77 kDa
Note	仅供科研使用

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