Rabbit Anti-S13A5/SLC13A5 Polyclonal Antibody
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产品编号
PAV3516
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别名
solute carrier family 13 member 5, DEE25, EIEE25, INDY, NACT, mIndy
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | solute carrier family 13 member 5, DEE25, EIEE25, INDY, NACT, mIndy |
| Catalog Number | PAV3516 |
| Product Description | Rabbit polyclonal antibody raised against human SLC13A5 (Na/citrate cotransporter). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | SLC13A5 |
| Species | Human, Mouse, Rat |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 转运蛋白 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | This gene encodes a protein belonging to the solute carrier family 13 group of proteins. This family member is a sodium-dependent citrate cotransporter that may regulate metabolic processes. Mutations in this gene cause early infantile epileptic encephalopathy 25. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2014] |
| Immunogen | This antibody was raised against from part region of human SLC13A5 protein (UniProt: Q86YT5) |
| Application | WB |
| Recommended Dilution | WB 1:500-2000 |
| Gene ID | 284111 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse, Rat |
| Predicted Molecular Weight | ≈63.1 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 63.1 kDa |
| Cross-reactivity | Human, Mouse, Rat |
| Uniprot ID | Q86YT5 |
| Note | Gene ID: 284111; UniProt: Q86YT5; Chromosome: 17p13.1; Predicted MW: 63.1 kDa |
| Function | High-affinity sodium/citrate cotransporter that mediates the entry of citrate into cells, which is a critical participant of biochemical pathways. May function in various metabolic processes in which citrate has a critical role such as energy production (Krebs cycle), fatty acid synthesis, cholesterol synthesis, glycolysis, and gluconeogenesis. Transports citrate into the cell in a Na(+)-dependent manner, recognizing the trivalent form of citrate (physiological pH) rather than the divalent form. Can recognize succinate as a substrate, but its affinity for succinate is several fold lower than for citrate. The stoichiometry is probably 4 Na(+) for each carboxylate, irrespective of whether the translocated substrate is divalent or trivalent, rendering the process electrogenic. Involved in the regulation of citrate levels in the brain (By similarity). |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human SLC13A5 Polyclonal Antibody |
| Target | SLC13A5 |
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