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Rabbit Anti-RM45/MRPL45 Polyclonal Antibody
Rabbit Anti-RM45/MRPL45 Polyclonal Antibody

Rabbit Anti-RM45/MRPL45 Polyclonal Antibody

产品编号

PAV3409

别名

mitochondrial ribosomal protein L45, L45mt, MRP-L45, Mba1, mL45

目录价格

InquiryRMB

规格
  • 100ul
产品介绍
Aliasmitochondrial ribosomal protein L45, L45mt, MRP-L45, Mba1, mL45
Catalog NumberPAV3409
Product DescriptionRabbit polyclonal antibody raised against human MRPL45 (Large ribosomal subunit protein mL45). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml.
Molecular NameMRPL45
SpeciesHuman
HostRabbit
Size100ul
ClonityPolyclonal
Protein Family翻译与核糖体
Concentration1 mg/ml
Purificationaffinity-chromatography
Formulationsupply in PBS containing 50% glycerol, and 0.02% sodium azide.
BackgroundMammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Alternative splicing results in multiple transcript variants. Pseudogenes corresponding to this gene are found on chromosomes 2p and 17q. [provided by RefSeq, May 2013]
ImmunogenThis antibody was raised against from part region of human MRPL45 protein (UniProt: Q9BRJ2)
ApplicationWB, ELISA
Recommended DilutionWB 1:500-2000 ELISA 1:5000-20000
Gene ID84311
TagUnconjugated
Cross-reactivityHuman
Predicted Molecular Weight≈35.4 kDa
Storage ConditionStore at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles.
Shipping ConditionThis product is shipped on blue ice.
Molecular Weight35.4 kDa
Cross-reactivityHuman
Uniprot IDQ9BRJ2
NoteGene ID: 84311; UniProt: Q9BRJ2; Chromosome: 17q12; Predicted MW: 35.4 kDa
FunctionComponent of the mitochondrial large ribosomal subunit (mt-LSU). Within the mitochondrial ribosomes, required to direct the nascent polypeptide toward the tunnel exit and position the exit at a distance from the membrane surface.
Product Declaration本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。
Product Full NameRabbit Anti-Human MRPL45 Polyclonal Antibody
TargetMRPL45

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