Rabbit Anti-TIMD4 Polyclonal Antibody
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产品编号
PAV4035
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别名
T cell immunoglobulin and mucin domain containing 4, SMUCKLER, TIM4
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | T cell immunoglobulin and mucin domain containing 4, SMUCKLER, TIM4 |
| Catalog Number | PAV4035 |
| Product Description | Rabbit polyclonal antibody raised against human TIMD4 (T-cell immunoglobulin and mucin domain-containing protein 4). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | TIMD4 |
| Species | Human, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 其他免疫分子 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | Enables phosphatidylserine binding activity. Involved in apoptotic cell clearance. Is active in plasma membrane. [provided by Alliance of Genome Resources, Jun 2026] |
| Immunogen | This antibody was raised against from part region of human TIMD4 protein (UniProt: Q96H15) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 91937 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse |
| Predicted Molecular Weight | ≈41.6 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 41.6 kDa |
| Cross-reactivity | Human, Mouse |
| Uniprot ID | Q96H15 |
| Note | Gene ID: 91937; UniProt: Q96H15; Chromosome: 5q33.3; Predicted MW: 41.6 kDa |
| Function | Phosphatidylserine receptor that plays different role in immune response including phagocytosis of apoptotic cells and T-cell regulation. Involved in efferocytosis, the process by which apoptotic cells are removed by phagocytic cells by promoting the engulfment of apoptotic cells or exogenous particles. Mechanistically, acts by securing apoptotic cells to phagocytes through direct binding to phosphatidylserine present on apoptotic cells, while other engulfment receptors such as MERTK efficiently recognize apoptotic cells and mediate their ingestion. Controls T-cell activation in a bimodal fashion, decreasing the activation of naive T-cells by inducing cell cycle arrest, while increasing proliferation of activated T-cells by activating AKT1 and ERK1/2 phosphorylations and subsequent signaling pathways (By similarity). |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human TIMD4 Polyclonal Antibody |
| Target | TIMD4 |
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