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Rabbit Anti-RL7A/RPL7A Polyclonal Antibody
Rabbit Anti-RL7A/RPL7A Polyclonal Antibody

Rabbit Anti-RL7A/RPL7A Polyclonal Antibody

产品编号

PAV3395

别名

ribosomal protein L7a, L7A, SURF3, TRUP, eL8

目录价格

InquiryRMB

规格
  • 100ul
产品介绍
Aliasribosomal protein L7a, L7A, SURF3, TRUP, eL8
Catalog NumberPAV3395
Product DescriptionRabbit polyclonal antibody raised against human RPL7A (Large ribosomal subunit protein eL8). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml.
Molecular NameRPL7A
SpeciesHuman, Mouse, Rat
HostRabbit
Size100ul
ClonityPolyclonal
Protein Family翻译与核糖体
Concentration1 mg/ml
Purificationaffinity-chromatography
Formulationsupply in PBS containing 50% glycerol, and 0.02% sodium azide.
BackgroundCytoplasmic ribosomes, organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L7AE family of ribosomal proteins. It can interact with a subclass of nuclear hormone receptors, including thyroid hormone receptor, and inhibit their ability to transactivate by preventing their binding to their DNA response elements. This gene is included in the surfeit gene cluster, a group of very tightly linked genes that do not share sequence similarity. It is co-transcribed with the U24, U36a, U36b, and U36c small nucleolar RNA genes, which are located in its second, fifth, fourth, and sixth introns, respectively. This gene rearranges with the trk proto-oncogene to form the chimeric oncogene trk-2h, which encodes an oncoprotein consisting of the N terminus of ribosomal protein L7a fused to the receptor tyrosine kinase domain of trk. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]
ImmunogenThis antibody was raised against from part region of human RPL7A protein (UniProt: P62424)
ApplicationWB, ELISA
Recommended DilutionWB 1:500-2000 ELISA 1:5000-20000
Gene ID6130
TagUnconjugated
Cross-reactivityHuman, Mouse, Rat
Predicted Molecular Weight≈30.0 kDa
Storage ConditionStore at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles.
Shipping ConditionThis product is shipped on blue ice.
Molecular Weight30.0 kDa
Cross-reactivityHuman, Mouse, Rat
Uniprot IDP62424
NoteGene ID: 6130; UniProt: P62424; Chromosome: 9q34.2; Predicted MW: 30.0 kDa
FunctionComponent of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
Product Declaration本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。
Product Full NameRabbit Anti-Human RPL7A Polyclonal Antibody
TargetRPL7A

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