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Rabbit Anti-PCDGB/PCDHGA11 Polyclonal Antibody
Rabbit Anti-PCDGB/PCDHGA11 Polyclonal Antibody

Rabbit Anti-PCDGB/PCDHGA11 Polyclonal Antibody

产品编号

PAV2962

别名

protocadherin gamma subfamily A, 11, PCDH-GAMMA-A11

目录价格

InquiryRMB

规格
  • 100ul
产品介绍
Aliasprotocadherin gamma subfamily A, 11, PCDH-GAMMA-A11
Catalog NumberPAV2962
Product DescriptionRabbit polyclonal antibody raised against human PCDHGA11 (Protocadherin gamma-A11). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml.
Molecular NamePCDHGA11
SpeciesHuman
HostRabbit
Size100ul
ClonityPolyclonal
Protein Family细胞黏附
Concentration1 mg/ml
Purificationaffinity-chromatography
Formulationsupply in PBS containing 50% glycerol, and 0.02% sodium azide.
BackgroundThis gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes. [provided by RefSeq, Jul 2008]
ImmunogenThis antibody was raised against from part region of human PCDHGA11 protein (UniProt: Q9Y5H2)
ApplicationWB
Recommended DilutionWB 1:500-2000
Gene ID56105
TagUnconjugated
Cross-reactivityHuman
Predicted Molecular Weight≈101.5 kDa
Storage ConditionStore at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles.
Shipping ConditionThis product is shipped on blue ice.
Molecular Weight101.5 kDa
Cross-reactivityHuman
Uniprot IDQ9Y5H2
NoteGene ID: 56105; UniProt: Q9Y5H2; Chromosome: 5q31.3; Predicted MW: 101.5 kDa
FunctionPotential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.
Product Declaration本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。
Product Full NameRabbit Anti-Human PCDHGA11 Polyclonal Antibody
TargetPCDHGA11

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