Rabbit Anti-NOC4L Polyclonal Antibody
-
产品编号
PAV2550
-
别名
nucleolar complex associated 4 homolog, NET49, NOC4, UTP19
-
目录价格
InquiryRMB
-
规格
- 100ul
产品介绍
| Alias | nucleolar complex associated 4 homolog, NET49, NOC4, UTP19 |
| Catalog Number | PAV2550 |
| Product Description | Rabbit polyclonal antibody raised against human NOC4L (Nucleolar complex protein 4 homolog). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | NOC4L |
| Species | Human |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 翻译与核糖体 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | Enables RNA binding activity. Predicted to be involved in rRNA processing. Located in nucleolus. [provided by Alliance of Genome Resources, Jun 2026] |
| Immunogen | This antibody was raised against from part region of human NOC4L protein (UniProt: Q9BVI4) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 79050 |
| Tag | Unconjugated |
| Cross-reactivity | Human |
| Predicted Molecular Weight | ≈58.5 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 58.5 kDa |
| Cross-reactivity | Human |
| Uniprot ID | Q9BVI4 |
| Note | Gene ID: 79050; UniProt: Q9BVI4; Chromosome: 12q24.33; Predicted MW: 58.5 kDa |
| Function | Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. Required for the translation of mRNAs related to activation of regulatory and conventional T cells but is not essential for global translation in regulatory T cells (By similarity). Ensures correct nucleolar localization of small ribosomal subunit processome member EMG1 as part of a complex with NOP14 and UTP14A. Blocks TLR4 endocytosis, causing inhibition of the TICAM1/TRIF signaling pathway (By similarity). This leads to reduced production of inflammatory cytokines which ameliorates local and systemic inflammation and influences insulin sensitivity (By similarity). Inhibits SIRT1-mediated deacetylation of TP53/p53. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human NOC4L Polyclonal Antibody |
| Target | NOC4L |
- 联系我们
- 电话：400-621-6806
- 手机：13116038708（微信）
- 邮箱：info@kmdbioscience.com
- 地址：天津市武清开发区和畅路6号10号厂房108室
-
销售微信
-
官方公众号
-
400-621-6806 -
3599163699 -
周一至周五 9:00-18:00 -
-
0
-
