Rabbit Anti-TPP1 Polyclonal Antibody
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产品编号
PAV4105
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别名
tripeptidyl peptidase 1, CLN2, GIG1, LPIC, SCAR7, TPP-1
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | tripeptidyl peptidase 1, CLN2, GIG1, LPIC, SCAR7, TPP-1 |
| Catalog Number | PAV4105 |
| Product Description | Rabbit polyclonal antibody raised against human TPP1 (Tripeptidyl-peptidase 1). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | TPP1 |
| Species | Human, Rat, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 蛋白酶 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | This gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome. [provided by RefSeq, Jul 2008] |
| Immunogen | This antibody was raised against from part region of human TPP1 protein (UniProt: O14773) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 1200 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Rat, Mouse |
| Predicted Molecular Weight | ≈61.2 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 61.2 kDa |
| Cross-reactivity | Human, Rat, Mouse |
| Uniprot ID | O14773 |
| Note | Gene ID: 1200; UniProt: O14773; Chromosome: 11p15.4; Predicted MW: 61.2 kDa |
| Function | Lysosomal serine protease with tripeptidyl-peptidase I activity. May act as a non-specific lysosomal peptidase which generates tripeptides from the breakdown products produced by lysosomal proteinases. Requires substrates with an unsubstituted N-terminus. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human TPP1 Polyclonal Antibody |
| Target | TPP1 |
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