Rabbit Anti-NR2E3 Polyclonal Antibody
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产品编号
PAV2595
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别名
nuclear receptor subfamily 2 group E member 3, ESCS, ESCS1, PNR, RNR, RP37, rd7
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | nuclear receptor subfamily 2 group E member 3, ESCS, ESCS1, PNR, RNR, RP37, rd7 |
| Catalog Number | PAV2595 |
| Product Description | Rabbit polyclonal antibody raised against human NR2E3 (Photoreceptor-specific nuclear receptor). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | NR2E3 |
| Species | Human, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 核受体 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | This protein is part of a large family of nuclear receptor transcription factors involved in signaling pathways. Nuclear receptors have been shown to regulate pathways involved in embryonic development, as well as in maintenance of proper cell function in adults. Members of this family are characterized by discrete domains that function in DNA and ligand binding. This gene encodes a retinal nuclear receptor that is a ligand-dependent transcription factor. Defects in this gene are a cause of enhanced S cone syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] |
| Immunogen | This antibody was raised against from part region of human NR2E3 protein (UniProt: Q9Y5X4) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 10002 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse |
| Predicted Molecular Weight | ≈44.7 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 44.7 kDa |
| Cross-reactivity | Human, Mouse |
| Uniprot ID | Q9Y5X4 |
| Note | Gene ID: 10002; UniProt: Q9Y5X4; Chromosome: 15q23; Predicted MW: 44.7 kDa |
| Function | Orphan nuclear receptor of retinal photoreceptor cells. Transcriptional factor that is an activator of rod development and repressor of cone development. Binds the promoter region of a number of rod- and cone-specific genes, including rhodopsin, M- and S-opsin and rod-specific phosphodiesterase beta subunit. Enhances rhodopsin expression. Represses M- and S-cone opsin expression. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human NR2E3 Polyclonal Antibody |
| Target | NR2E3 |
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