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Recombinant Human EGFR Protein, Fc Tag

Recombinant Human EGFR Protein, Fc Tag

Recombinant Human EGFR Protein, Fc Tag

产品编号

KMH1013

别名

ERBB, HER1, mENA, ERBB1, PIG61, NISBD2, epidermal growth factor receptor

规格

50ug
100ug

DATASHEET COA

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产品介绍

Alias	ERBB, HER1, mENA, ERBB1, PIG61, NISBD2, epidermal growth factor receptor
Catalog Number	KMH1013
Molecular Name	EGFR
Species	Human
Host	Mammalian cells
Size	50ug, 100ug
Protein Family	Other protein
Purity	≥90% as determined by SDS-PAGE
Purification	Affinity Purification
Endotoxin	< 1.0 EU per ug of the protein as determined by the LAL method.
Formulation	PBS
Background	As a member of the epidermal growth factor receptor tyrosine kinases subfamily, EGF R is a type Ⅰ transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR signaling plays a crucial role in the regulation of cell proliferation, survival and differentiation. Binding of a ligand induces EGFR homo- or hetero- dimerization, initiates subsequent tyrosine autophosphorylation and various downstream pathways (MAPK, PI3K/PKB and STAT). In addition, EGFR signaling has been shown to exert actions on carcinogenesis and disease progression, and thus EGFR was proposed as a target for cancer therapy currently.
Storage Condition	Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping Condition	This product is shipped on ice packs or dry ice.
Molecular Weight	64.05 kDa
Note	仅供科研使用

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