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Rabbit Anti-PIGA Polyclonal Antibody
Rabbit Anti-PIGA Polyclonal Antibody

Rabbit Anti-PIGA Polyclonal Antibody

产品编号

PAV3038

别名

phosphatidylinositol glycan anchor biosynthesis class A, GPI3, MCAHS2, NEDEPH, PIG-A, PNH1

目录价格

InquiryRMB

规格
  • 100ul
产品介绍
Aliasphosphatidylinositol glycan anchor biosynthesis class A, GPI3, MCAHS2, NEDEPH, PIG-A, PNH1
Catalog NumberPAV3038
Product DescriptionRabbit polyclonal antibody raised against human PIGA (Phosphatidylinositol N-acetylglucosaminyltransferase subunit A). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml.
Molecular NamePIGA
SpeciesHuman, Mouse
HostRabbit
Size100ul
ClonityPolyclonal
Protein Family代谢酶
Concentration1 mg/ml
Purificationaffinity-chromatography
Formulationsupply in PBS containing 50% glycerol, and 0.02% sodium azide.
BackgroundThis gene encodes a protein required for synthesis of N-acetylglucosaminyl phosphatidylinositol (GlcNAc-PI), the first intermediate in the biosynthetic pathway of GPI anchor. The GPI anchor is a glycolipid found on many blood cells and which serves to anchor proteins to the cell surface. Paroxysmal nocturnal hemoglobinuria, an acquired hematologic disorder, has been shown to result from mutations in this gene. Alternate splice variants have been characterized. A related pseudogene is located on chromosome 12. [provided by RefSeq, Jun 2010]
ImmunogenThis antibody was raised against from part region of human PIGA protein (UniProt: P37287)
ApplicationWB, ELISA
Recommended DilutionWB 1:500-2000 ELISA 1:5000-20000
Gene ID5277
TagUnconjugated
Cross-reactivityHuman, Mouse
Predicted Molecular Weight≈54.1 kDa
Storage ConditionStore at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles.
Shipping ConditionThis product is shipped on blue ice.
Molecular Weight54.1 kDa
Cross-reactivityHuman, Mouse
Uniprot IDP37287
NoteGene ID: 5277; UniProt: P37287; Chromosome: Xp22.2; Predicted MW: 54.1 kDa
FunctionCatalytic subunit of the glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex that catalyzes the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol and participates in the first step of GPI biosynthesis.
Product Declaration本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。
Product Full NameRabbit Anti-Human PIGA Polyclonal Antibody
TargetPIGA

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