Rabbit Anti-PHX2A/PHOX2A Polyclonal Antibody
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产品编号
PAV3028
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别名
paired like homeobox 2A, ARIX, CFEOM2, FEOM2, PMX2A
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | paired like homeobox 2A, ARIX, CFEOM2, FEOM2, PMX2A |
| Catalog Number | PAV3028 |
| Product Description | Rabbit polyclonal antibody raised against human PHOX2A (Paired mesoderm homeobox protein 2A). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | PHOX2A |
| Species | Human, Rat, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 转录因子 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | The protein encoded by this gene contains a paired-like homeodomain most similar to that of the Drosophila aristaless gene product. The encoded protein plays a central role in development of the autonomic nervous system. It regulates the expression of tyrosine hydroxylase and dopamine beta-hydroxylase, two catecholaminergic biosynthetic enzymes essential for the differentiation and maintenance of the noradrenergic neurotransmitter phenotype. The encoded protein has also been shown to regulate transcription of the alpha3 nicotinic acetylcholine receptor gene. Mutations in this gene have been associated with autosomal recessive congenital fibrosis of the extraocular muscles. [provided by RefSeq, Jul 2008] |
| Immunogen | This antibody was raised against from part region of human PHOX2A protein (UniProt: O14813) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 401 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Rat, Mouse |
| Predicted Molecular Weight | ≈29.7 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 29.7 kDa |
| Cross-reactivity | Human, Rat, Mouse |
| Uniprot ID | O14813 |
| Note | Gene ID: 401; UniProt: O14813; Chromosome: 11q13.4; Predicted MW: 29.7 kDa |
| Function | May be involved in regulating the specificity of expression of the catecholamine biosynthetic genes. Involved in the development of several major noradrenergic neuron populations, including the locus coeruleus. Acts as a transcription activator/factor. Could maintain the noradrenergic phenotype (By similarity). |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human PHOX2A Polyclonal Antibody |
| Target | PHOX2A |
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