Rabbit Anti-P Polyclonal Antibody
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产品编号
PAV2886
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别名
OCA2 melanosomal transmembrane protein, BEY, BEY1, BEY2, BOCA, D15S12, EYCL, EYCL2, EYCL3
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | OCA2 melanosomal transmembrane protein, BEY, BEY1, BEY2, BOCA, D15S12, EYCL, EYCL2, EYCL3 |
| Catalog Number | PAV2886 |
| Product Description | Rabbit polyclonal antibody raised against human OCA2 (P protein). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | OCA2 |
| Species | Human |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 其他信号分子 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | This gene encodes the human homolog of the mouse p (pink-eyed dilution) gene. The encoded protein is believed to be an integral membrane protein involved in small molecule transport, specifically tyrosine, which is a precursor to melanin synthesis. It is involved in mammalian pigmentation, where it may control skin color variation and act as a determinant of brown or blue eye color. Mutations in this gene result in type 2 oculocutaneous albinism. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014] |
| Immunogen | This antibody was raised against from part region of human OCA2 protein (UniProt: Q04671) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 4948 |
| Tag | Unconjugated |
| Cross-reactivity | Human |
| Predicted Molecular Weight | ≈92.8 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 92.8 kDa |
| Cross-reactivity | Human |
| Uniprot ID | Q04671 |
| Note | Gene ID: 4948; UniProt: Q04671; Chromosome: 15q12-q13.1; Predicted MW: 92.8 kDa |
| Function | Contributes to a melanosome-specific anion (chloride) current that modulates melanosomal pH for optimal tyrosinase activity required for melanogenesis and the melanosome maturation. One of the components of the mammalian pigmentary system. May serve as a key control point at which ethnic skin color variation is determined. Major determinant of brown and/or blue eye color. Seems to regulate the post-translational processing of tyrosinase, which catalyzes the limiting reaction in melanin synthesis (By similarity). |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human OCA2 Polyclonal Antibody |
| Target | OCA2 |
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