Recombinant Human CD209 Protein, Fc Tag
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产品编号
KMH373
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别名
CDSIGN, CLEC4L, DC SIGN, DC SIGN1, CD209 molecule
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目录价格
联系客服获取报价RMB
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规格
- 50ug
- 100ug
产品介绍
| Alias | CDSIGN, CLEC4L, DC SIGN, DC SIGN1, CD209 molecule |
| Catalog Number | KMH373 |
| Molecular Name | CD209 |
| Species | Human |
| Host | Mammalian cells |
| Size | 50ug, 100ug |
| Protein Family | CD molecule |
| Purity | ≥90% as determined by SDS-PAGE |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purification | Affinity Purification |
| Endotoxin | < 1.0 EU per ug of the protein as determined by the LAL method. |
| Formulation | PBS |
| Background | Human Dendritic Cell-specific ICAM-3 Grabbing Non-integrin (DC-SIGN)/CD29 is a member of the C-type lectin family. The canonical DC-SIGN/CD29 isoform is a 46 kDa, 44 amino acid (aa) type II transmembrane protein. The extracellular region contains a Ca2+-dependent carbohydrate-binding lectin domain. Multiple human DC-SIGN/CD29 splice forms exist, generating both membrane-bound and soluble forms. DC-SIGN/CD29 is not well conserved between mouse and human, with the extracellular domain sharing only 63% aa identity. The DC-SIGN/CD29 lectin domain binds mannose oligosaccharides on pathogens including HIV as well as self glycoproteins including ICAMs. DC-SIGN/CD29 binds to butyrophilin 2A1 and this interaction can be blocked by HIV pp12. DC-SIGN/CD29 is expressed on dendritic cells (DC) and inflammatory macrophages and contributes to antigen presentation. |
| Application | WB, ELISA |
| Recommended Dilution | ELISA: 1:100-1:1000 |
| Cross-reactivity | No cross-reactivity with other antigens or proteins. |
| Predicted Molecular Weight | 63.06 kDa |
| Predicted N Terminus | Glu 20 |
| Reconstitution | Not applicable. The product is supplied as a ready-to-use liquid formulation. |
| Storage Condition | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |
| Remarks | 收到产品后请立即按保存条件储存；使用前短暂离心，使内容物集中于管底；避免反复冻融。 |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Stability | Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
| Molecular Weight | 63.06 kDa |
| Cross-reactivity | No cross-reactivity with other antigens or proteins. |
| Uniprot ID | Q9NNX6 |
| Note | 仅供科研使用 |
| ELISA IC50(ppb) | ≥ 1:1000 |
| Function | Human Dendritic Cell-specific ICAM-3 Grabbing Non-integrin (DC-SIGN)/CD29 is a member of the C-type lectin family. The canonical DC-SIGN/CD29 isoform is a 46 kDa, 44 amino acid (aa) type II transmembrane protein. The extracellular region contains a Ca2+-dependent carbohydrate-binding lectin domain. Multiple human DC-SIGN/CD29 splice forms exist, generating both membrane-bound and soluble forms. DC-SIGN/CD29 is not well conserved between mouse and human, with the extracellular domain sharing only 63% aa identity. The DC-SIGN/CD29 lectin domain binds mannose oligosaccharides on pathogens including HIV as well as self glycoproteins including ICAMs. DC-SIGN/CD29 binds to butyrophilin 2A1 and this interaction can be blocked by HIV pp12. DC-SIGN/CD29 is expressed on dendritic cells (DC) and inflammatory macrophages and contributes to antigen presentation. |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
| Temperature Range | -20℃ ~ -80℃ |
| Solubility | 产品为即用型液体，无需复溶。 |
| Appearance | Liquid |
| Product Full Name | Recombinant Human CD209 Protein |
| Preservative Solution | PBS |
| Usage Method | 冻干粉请按“复溶”说明用无菌去离子水复溶后使用，液体产品可直接使用；具体工作浓度请参考“推荐稀释比例”。 |
| Target | CD209 |
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