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CyCMV (strain OT-1) GB Protein, Fc Tag
CyCMV (strain OT-1) GB Protein, Fc Tag

CyCMV (strain OT-1) GB Protein, Fc Tag

产品编号

KMP4419

别名

巨细胞病毒巨细胞病毒包膜糖蛋白, CyCMV GB, Glycoprotein B, CyCMV GB Protein

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias巨细胞病毒巨细胞病毒包膜糖蛋白, CyCMV GB, Glycoprotein B, CyCMV GB Protein
Catalog NumberKMP4419
Product DescriptionThe CyCMV (strain OT-1) GB Protein(KMP4419) is produced in HEK293 Cells. A DNA sequence encoding the macaca fascicularis cytomegalovirus (CyCMV)(strain OT-1) glycoprotein B(gB) (ADV35145.1) (Met1-Asp680, with cleavage site mutated ‘RHKR’ to ‘TTQT’) was expressed with the Fc region of human IgG1 at the C-terminus.
Molecular NameCyCMV GB
SpeciesCyCMV
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>90% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
Formulation40mM PB, 500mM NaCl, pH7.4
BackgroundCoronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. The coronavirus N protein is required for coronavirus RNA synthesis and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is the most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to the formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of the N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
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