HCMV gB Protein, Fc Tag
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产品编号
VAG349
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别名
Cytomegalovirus
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规格
- 20ug
- 100ug
Alias | Cytomegalovirus |
Catalog Number | VAG349 |
Molecular Name | HCMV |
Species | HCMV |
Host | HEK293 Cells |
Size | 20ug, 100ug |
Purity | >80%, determined by SDS-PAGE |
Endotoxin | <1.0 EU/ug determined by the LAL method |
Formulation | Lyophilized from sterile PBS, pH 7.4, and 0.01% Tween80 are added as protectants |
Predicted N Terminus | Asn 25 |
Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Shipping Condition | Lyophilized powder will be shipped on at ambient temperature. Please contact our customer service to get specific information about the shipping condition of your order. |
gB(糖蛋白B)是巨细胞病毒(HCMV)包膜的关键蛋白,介导病毒与宿主细胞膜融合及进入,是中和抗体的主要靶点。
Fc标签可延长蛋白半衰期(通过结合Fc受体),并便于Protein A/G纯化或免疫检测(如ELISA、流式细胞术)。
是的,gB是HCMV疫苗研发的核心抗原,可诱导中和抗体及T细胞免疫应答。
蛋白在哺乳动物细胞(如HEK293)中表达,保留天然糖基化修饰,更接近病毒天然构象。
可通过细胞-细胞融合实验或基于荧光染料的脂质体融合试验验证其功能活性。