SARS S2 Protein
- 
									
产品编号
KMP4903
 - 
									
别名
冠状病毒刺突蛋白S2, SARS S2, Spike2 Protein, SARS S2 Protein
 - 
									
规格
- 50ug
 - 100ug
 - 200ug
 
 
| Catalog Number | KMP4903 | 
| Alias | 冠状病毒刺突蛋白S2, SARS S2, Spike2 Protein, SARS S2 Protein | 
| Size | 50ug, 100ug, 200ug | 
| Product Description | The SARS S2 Protein(KMP4903) is produced in Insect Cells. A DNA sequence encoding the SARS-CoV spike S2 (NP_828851.1) (Ser668-Pro1195) was expressed with a C-terminal polyhistidine tag. | 
| Molecular Name | SARS S2 | 
| Species | SARS | 
| Host | Insect Cells | 
| Purity | >95% as determined by SDS-PAGE | 
| Purification | Affinity purification | 
| Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. | 
| Formulation | 50mM Tris, 500mM NaCl | 
| Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. | 
| Endotoxin | <1.0 EU/ug determined by the LAL method | 
S2包含融合肽(FP)、七肽重复区1/2(HR1/HR2),介导病毒与宿主细胞膜融合,是泛冠状病毒抑制剂(如EK1多肽)的靶点。
需在酸性pH条件下激活,通过脂质体融合实验或细胞-细胞融合模型验证其功能。
是的,HR1-HR2复合物可形成六螺旋束(6-HB),是X射线晶体学或冷冻电镜的热门靶点。
通过离子交换层析(如SP柱)或疏水相互作用层析(HIC)纯化,依赖蛋白表面电荷和疏水性。
是的,S2区域在冠状病毒中高度保守,可筛选靶向融合过程的抑制剂。
							
							
							
							
						
								0