RVFV (strain MP12) GP Protein, His Tag_天津卡梅德科技发展有限公司

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RVFV (strain MP12) GP Protein, His Tag

RVFV (strain MP12) GP Protein, His Tag

产品编号

KMP4892

别名

裂谷热病毒包膜糖蛋白, RVFV GP, Glycoprotein, RVFV GP Protein

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Catalog Number	KMP4892
Alias	裂谷热病毒包膜糖蛋白, RVFV GP, Glycoprotein, RVFV GP Protein
Size	50ug, 100ug, 200ug
Product Description	The RVFV (strain MP12) GP Protein(KMP4892) is produced in Insect Cells. A DNA sequence encoding the Rift Valley fever virus (RVFV) (strain MP12) Gc (ABD38821.1) (Cys691-Ser1139) was expressed with a polyhistidine tag at the N-terminus.
Molecular Name	RVFV GP
Species	RVFV
Host	Insect Cells
Purity	>90% as determined by SDS-PAGE
Purification	Affinity purification
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Formulation	20mM Tris, 150mM NaCl, pH8.5
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Endotoxin	<1.0 EU/ug determined by the LAL method

FAQ

Q1-GP蛋白的功能是什么？

GP介导病毒与宿主细胞（如肝细胞）结合，并通过膜融合促进病毒入侵，是疫苗和药物靶点。
Q2-MP12株的安全性如何？

MP12是减毒活疫苗株，其GP蛋白可用于研究免疫保护机制，操作需在BSL-2实验室进行。
Q3-如何验证GP的膜融合活性？

通过脂质体融合实验或细胞-细胞融合实验（如表达GP的效应细胞与靶细胞共培养）。
Q4-是否支持动物免疫实验？

是的，已用于小鼠和绵羊模型，诱导中和抗体并评估抗病毒效果。
Q5-蛋白的糖基化修饰是否保留？

哺乳动物细胞（如HEK293）表达保留N-糖基化，昆虫细胞表达可能简化糖链结构。

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