HIV (group M, subtype B, strain HXB2) p24 Protein, His Tag_天津卡梅德科技发展有限公司

>>

>>

>>

>

HIV (group M, subtype B, strain HXB2) p24 Protein, His Tag

HIV (group M, subtype B, strain HXB2) p24 Protein, His Tag

产品编号

KMP4802

别名

人类免疫缺陷病毒衣壳蛋白p24, HIV p24, Capsid Protein p24, HIV p24 Protein

规格

50ug
100ug
200ug

DATASHEET MSDS

立即询价加入询价列表大包装定制

产品介绍

Alias	人类免疫缺陷病毒衣壳蛋白p24, HIV p24, Capsid Protein p24, HIV p24 Protein
Catalog Number	KMP4802
Product Description	The HIV (group M, subtype B, strain HXB2) p24 Protein(KMP4802) is produced in E. coli. A DNA sequence encoding the HIV1 Gag-P24 (subtype B) (AAB50258.1) (Pro133-Leu363) was expressed with a polyhistidine tag at the C-terminus.
Molecular Name	HIV p24
Species	HIV
Host	E. coli
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	The influenza viral Hemagglutinin (HA) protein is a homotrimer with a receptor binding pocket on the globular head of each monomer.HA has at least 18 different antigens. These subtypes are named H1 through H18.HA has two functions. Firstly, it allows the recognition of target vertebrate cells, accomplished through the binding to these cells' sialic acid-containing receptors. Secondly, once bound it facilitates the entry of the viral genome into the target cells by causing the fusion of the host endosomal membrane with the viral membrane. The influenza virus Hemagglutinin (HA) protein is translated in cells as a single protein, HA, or hemagglutinin precursor protein. For viral activation, hemagglutinin precursor protein (HA) must be cleaved by a trypsin-like serine endoprotease at a specific site, normally coded for by a single basic amino acid (usually arginine) between the HA1 and HA2 domains of the protein. After cleavage, the two disulfide-bonded protein domains produce the mature form of the protein subunits as a prerequisite for the conformational change necessary for fusion and hence viral infectivity.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.

FAQ

Q1-p24蛋白的生物学功能是什么？

p24是HIV衣壳蛋白，包裹病毒RNA形成核心结构，并在病毒成熟过程中起组装调控作用。
Q2-HXB2株为何是研究热点？

HXB2是HIV-1的实验室参考株，其基因序列高度标准化，广泛用于分子生物学和诊断试剂开发。
Q3-该蛋白能否用于病毒载量检测？

是的，p24是早期感染标志物，可通过ELISA或化学发光法检测血清中的抗原水平。
Q4-His标签如何去除？

可提供TEV蛋白酶切割位点定制服务，切除His标签后需重新纯化（需额外订购）。
Q5-储存条件对p24稳定性有何影响？

-80℃保存可维持长期稳定性，反复冻融易导致聚集，建议分装后使用。

推荐产品

400-621-6806
614353794
周一至周五 9:00-18:00
0