DENV (type 2, strain New Guinea C/PUO-218 hybrid) E Protein (ECD), His Tag
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产品编号
VAG295
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别名
DENV, Dengue Virus
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规格
- 50ug
- 100ug
Alias | DENV, Dengue Virus |
Catalog Number | VAG295 |
Molecular Name | DENV |
Species | Dengue Virus |
Host | Baculovirus-Insect Cells |
Size | 50ug, 100ug |
Purity | >90%, determined by SDS-PAGE |
Endotoxin | <1.0 EU/ug determined by the LAL method |
Formulation | Lyophilized from sterile PBS, pH 7.4, and 0.01% Tween80 are added as protectants |
Predicted N Terminus | Met |
Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Shipping Condition | Lyophilized powder will be shipped on at ambient temperature. Please contact our customer service to get specific information about the shipping condition of your order. |
E蛋白介导病毒与宿主细胞受体结合及膜融合,其ECD是中和抗体的主要靶标。
经非还原SDS-PAGE验证,E蛋白以二聚体形式存在,二硫键(Cys-30-Cys-30)稳定。
是的,作为亚单位疫苗抗原或载体展示蛋白,诱导交叉保护性免疫应答。
提供质谱分析报告,确认Asn-67和Asn-153位点的N-糖基化修饰。
使用FcγRIIB敲除细胞系进行感染增强实验,排除非特异性Fc介导的ADE效应。