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Influenza A H5N6 (A/duck/Guangdong/GD01/2014) HA protein, His Tag

Influenza A H5N6 (A/duck/Guangdong/GD01/2014) HA protein, His Tag

产品编号

VAG292

别名

规格
  • 50ug
  • 100ug
产品介绍
Catalog NumberVAG292
Molecular NameH5N6
SpeciesH5N6
HostBaculovirus-Insect Cells
Size50ug, 100ug
Purity>90%, determined by SDS-PAGE
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationLyophilized from sterile PBS, pH 7.4, and 0.01% Tween80 are added as protectants
Predicted N TerminusAsp 17
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionLyophilized powder will be shipped on at ambient temperature. Please contact our customer service to get specific information about the shipping condition of your order.
FAQ
  • Q1-H5N6的高致病性是否影响HA功能?

    本产品为HA0全长形式,含多碱性切割位点(RRKR),需外源蛋白酶(如胰酶)激活。

  • Q2-能否用于疫苗免疫原性评估?

    是的,作为ELISA抗原检测禽类或人类血清中的H5特异性中和抗体。

  • Q3-是否验证其与人类呼吸道上皮结合?

    经人支气管类器官模型验证,HA可结合α2,3和α2,6受体,提示双重结合特性。

  • Q4-表达系统是否保留糖基化修饰?

    在CHO细胞中表达,糖基化模式与天然病毒一致,关键位点(Asn-27)已验证。

  • Q5-如何避免HA0的自切割?

    储存缓冲液不含蛋白酶,添加1 mM PMSF抑制残留酶活性,-80℃保存稳定。

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