Inactivated Human Cytomegalovirus Antigen
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产品编号
VAG363
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别名
灭活巨细胞病毒抗原
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规格
- 1ml
产品介绍
| Alias | 灭活巨细胞病毒抗原 |
| Catalog Number | VAG363 |
| Product Description | This antigen was purfied from native inactivated Human Cytomegalovirus(CMV) AD169 strain. |
| Molecular Name | CMV |
| Species | Virus |
| Host | NHDF Cell |
| Size | 1ml |
| Protein Family | Human Betaherpesvirus 5 Antigen, CMV |
| Purity | ≥90%, determined by SDS-PAGE |
| Purification | Density Gradient Centrifugation |
| Formulation | 0.1M PBS, PH 7 |
| Background | Human cytomegalovirus is the type species of the virus genus Cytomegalovirus, which belongs to the Betaherpesvirinae subfamily. HCMV infections are frequently associated with the salivary glands. Congenital cytomegalovirus infection can lead to significant morbidity and even death. After infection, HCMV remains latent within the body throughout life and can be reactivated at any time. Eventually, it may cause mucoepidermoid carcinoma and possibly other malignancies such as prostate cancer and breast cancer. |
| Application | ELISA, WB |
| Storage Condition | Store the product under sterile conditions after opening at -80℃. Avoid repeated freeze-thaw cycles. |
| Shipping Condition | This product is shipped on dry ice. |
FAQ
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Q1-抗原包含HCMV的哪些蛋白成分？
包含主要免疫原性蛋白（如pp65、gB），可根据需求定制全病毒裂解物或纯化单一蛋白。
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Q2-如何避免与其他疱疹病毒（如EBV）的交叉反应？
通过亲和层析去除交叉反应表位，并采用特异性单抗验证抗原纯度。
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Q3-是否适用于T细胞免疫应答研究？
是的，可用于ELISpot或流式细胞术检测HCMV特异性T细胞活性。
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Q4-灭活抗原的残留DNA含量如何控制？
通过DNase处理和超滤技术，确保残留DNA≤10 ng/剂，符合疫苗生产标准。
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Q5-能否用于移植患者术后CMV感染的监测？
可以，配合定量PCR或血清学检测，评估患者免疫状态及感染风险。
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