MOP2303
肿瘤坏死因子受体超家族成员1b, p75, TNFBR, Tnfr2, CD120b, TNF R2, TNFR80, TNFRII, Tnfr 1, TNF R75, TNF R II, TNF alphaR2, TNFalpha R2, tumor necrosis factor receptor superfamily, member 1b
| Catalog Number | MOP2303 |
| Alias | 肿瘤坏死因子受体超家族成员1b, p75, TNFBR, Tnfr2, CD120b, TNF R2, TNFR80, TNFRII, Tnfr 1, TNF R75, TNF R II, TNF alphaR2, TNFalpha R2, tumor necrosis factor receptor superfamily, member 1b |
| Size | 20ug, 50ug, 100ug, 200ug, 1mg |
| Product Description | MOP2303 Recombinant Mouse Tnfrsf1b Protein, C-hFc and His tag contains the mouse Tnfrsf1b(23-258 aa) was expressed in Mammalian cells. |
| Molecular Name | Tnfrsf1b |
| Product Introduction | Tnfrsf1b (MOP2303) 参与免疫反应和细胞凋亡过程。 |
| Molecular Weight | 66-76 kDa |
| Expression System | HEK293F Cells |
| Species | Mouse |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purity | ≥95% |
| SDS-PAGE |  |
| Purification | Affinity Purification |
| Uniprot ID | P25119 |
| Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. |
| Formulation | PBS |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Background | TNFR binds specifically to tumor necrosis factor (TNF) and blocks its interaction with cell surface TNF receptors. TNF is a naturally occurring cytokine that is involved in normal inflammatory and immune responses. It plays an important role in the inflammatory processes of rheumatoid arthritis (RA), polyarticular-course juvenile rheumatoid arthritis (JRA), and ankylosing spondylitis and the resulting joint pathology. Recombinant Human TNFR is a dimeric soluble form of the p75 TNF receptor that can bind to two TNF molecules. |
| Endotoxin | < 0.1 EU per ug |
| Protein Family | Other protein |
| Biological Activity | Measured by its ability to inhibit the TNF-alpha mediated cytotoxicity in the L‑929 mouse fibroblast cells in the presence of the metabolic inhibitor actinomycin D. in Lymphokines and Interferons, A Practical Approach. The ED50 forthis effect is 3-15 ng/m |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
通过优化表达条件、使用高质量的培养基和转染试剂，并通过纯化后检测蛋白的活性和纯度来确保蛋白质量。
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