Recombinant Mouse Tnf-alpha Protein, No tag
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产品编号
MOP2299
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别名
肿瘤坏死因子α, DIF, Tnfa, TNF a, TNFSF2, Tnlg1f, Tnfsf1a, TNFalpha, TNF alpha, tumor necrosis factor
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规格
- 20ug
- 50ug
- 100ug
- 200ug
- 1mg
Alias | 肿瘤坏死因子α, DIF, Tnfa, TNF a, TNFSF2, Tnlg1f, Tnfsf1a, TNFalpha, TNF alpha, tumor necrosis factor |
Catalog Number | MOP2299 |
Molecular Name | Tnf |
Molecular Weight | 17 kDa |
Size | 20ug, 50ug, 100ug, 200ug, 1mg |
Concentration | 联系销售经理获得最新批次的浓度 |
Purity | ≥95% |
SDS-PAGE | ![]() |
Product Description | MOP2299 Recombinant Mouse Tnf-alpha Protein, No tag contains the mouse Tnf(80-235 aa) was expressed in E. coli. |
Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. |
Formulation | PBS |
Shipping Condition | This product is shipped on ice packs or dry ice. |
Background | Tnf is secreted bymacrophages, monocytes, neutrophils, T-cells, NK- cells following theirstimulation by bacterial lipopolysaccharides. Cells expressing CD4 secrete TNF-alpha while CD8(+) cells secrete little or no TNF- alpha. Stimulatedperipheral neutrophilic granulocytes but also unstimulated cells and also anumber of transformed cell lines, astrocytes, microglial cells, smooth musclecells, and fibroblasts also secrete Tnf. Human milk also contains thisfactor. The synthesis of TNF-alpha is induced by many different stimuliincluding interferons, IL2, GM-CSF, SP, Bradykinin, Immune complexes,inhibitors of cyclooxygenase and PAF (platelet activating factor). |
Species | Mouse |
Protein Family | Other protein |
Purification | Affinity Purification |
Endotoxin | < 1.0 EU per ug |
Biological Activity | Recombinant Mouse TNF-alpha induces cytotoxicity in the L-929 mouse fibroblast cells in the presence of the metabolic inhibitor actinomycin D. The ED50 forthis effect is typically 29-116 pg/mL, corresponding to a specific activity of 8.62×10^6- 3.45×10^7 |
Uniprot ID | P06804 |
Product Declaration | 该产品仅供科研使用,不可直接用于人体或注射。 |
Display Peptides | E. coli |