Recombinant Mouse Tnf-alpha Protein, No tag_天津卡梅德科技发展有限公司

Recombinant Mouse Tnf-alpha Protein, No tag

产品编号

MOP2299

别名

肿瘤坏死因子α, DIF, Tnfa, TNF a, TNFSF2, Tnlg1f, Tnfsf1a, TNFalpha, TNF alpha, tumor necrosis factor

规格

20ug
50ug
100ug
200ug
1mg

DATASHEET MSDS

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产品介绍

Catalog Number	MOP2299
Alias	肿瘤坏死因子α, DIF, Tnfa, TNF a, TNFSF2, Tnlg1f, Tnfsf1a, TNFalpha, TNF alpha, tumor necrosis factor
Size	20ug, 50ug, 100ug, 200ug, 1mg
Product Description	MOP2299 Recombinant Mouse Tnf-alpha Protein, No tag contains the mouse Tnf(80-235 aa) was expressed in E. coli.
Molecular Name	Tnf
Product Introduction	Tnf (MOP2299) 是一种细胞因子，调节免疫反应及炎症反应，广泛参与许多疾病的免疫反应。
Molecular Weight	17 kDa
Expression System	E. coli
Species	Mouse
Concentration	联系销售经理获得最新批次的浓度
Purity	≥95%
SDS-PAGE
Purification	Affinity Purification
Uniprot ID	P06804
Storage Condition	Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles.
Formulation	PBS
Shipping Condition	This product is shipped on ice packs or dry ice.
Background	Tnf is secreted bymacrophages, monocytes, neutrophils, T-cells, NK- cells following theirstimulation by bacterial lipopolysaccharides. Cells expressing CD4 secrete TNF-alpha while CD8(+) cells secrete little or no TNF- alpha. Stimulatedperipheral neutrophilic granulocytes but also unstimulated cells and also anumber of transformed cell lines, astrocytes, microglial cells, smooth musclecells, and fibroblasts also secrete Tnf. Human milk also contains thisfactor. The synthesis of TNF-alpha is induced by many different stimuliincluding interferons, IL2, GM-CSF, SP, Bradykinin, Immune complexes,inhibitors of cyclooxygenase and PAF (platelet activating factor).
Endotoxin	< 1.0 EU per ug
Protein Family	Other protein
Biological Activity	Recombinant Mouse TNF-alpha induces cytotoxicity in the L-929 mouse fibroblast cells in the presence of the metabolic inhibitor actinomycin D. The ED50 forthis effect is typically 29-116 pg/mL, corresponding to a specific activity of 8.62×10^6- 3.45×10^7
Product Declaration	该产品仅供科研使用，不可直接用于人体或注射。