Recombinant Mouse Timp-1 Protein, C-His tag
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产品编号
MOP2297
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别名
金属基质金属蛋白酶抑制因子1, EPA, Clgi, Timp, TIMP 1, TPA S1, tissue inhibitor of metalloproteinase 1
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规格
- 20ug
 - 50ug
 - 100ug
 - 200ug
 - 1mg
 
 
| Catalog Number | MOP2297 | 
| Alias | 金属基质金属蛋白酶抑制因子1, EPA, Clgi, Timp, TIMP 1, TPA S1, tissue inhibitor of metalloproteinase 1 | 
| Size | 20ug, 50ug, 100ug, 200ug, 1mg | 
| Product Description | MOP2297 Recombinant Mouse Timp-1 Protein, C-His tag contains the mouse Timp1(Cys25-Arg205) was expressed in Mammalian cells. | 
| Molecular Name | Timp1 | 
| Product Introduction | Timp1 (MOP2297) 是一种金属蛋白酶抑制剂,参与调节细胞外基质的降解。 | 
| Molecular Weight | 32 kDa | 
| Expression System | HEK293F Cells | 
| Species | Mouse | 
| Concentration | 联系销售经理获得最新批次的浓度 | 
| Purity | ≥95% | 
| SDS-PAGE | ![]()  | 
| Purification | Affinity Purification | 
| Uniprot ID | P12032 | 
| Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. | 
| Formulation | PBS | 
| Shipping Condition | This product is shipped on ice packs or dry ice. | 
| Background | The tissue inhibitor of metalloproteinases (TIMP-1) is a glycoprotein with a molecular mass of about 28-kDa. The secreted protein consists of 184 amino acids, six disuilfide bonds and two glycosylation sites containing N-linked oligosaccharides. TIMP-1 specifically inhibits the extracellular-matrix-degrading metalloproteinases such as collagenase, gelatinase and stromelysin. It has no activity on mammalian membrane metallo-proteinases, procollagen peptidase, or on bacterial metalloproteinases such as thermolysin. | 
| Endotoxin | < 0.1 EU per ug | 
| Protein Family | Other protein | 
| Biological Activity | Measured by its ability to inhibit human MMP-2 cleavage of a fluorogenic peptide substrate McaPLGL-Dpa-ARNH2. The IC50 value is <3.5 nM, as measured underthe described conditions. | 
| Product Declaration | 该产品仅供科研使用,不可直接用于人体或注射。 | 
							
							
							
							
						
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