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Recombinant Mouse Timp-1 Protein, C-His tag

Recombinant Mouse Timp-1 Protein, C-His tag

产品编号

MOP2297

别名

金属基质金属蛋白酶抑制因子1, EPA, Clgi, Timp, TIMP 1, TPA S1, tissue inhibitor of metalloproteinase 1

规格
  • 20ug
  • 50ug
  • 100ug
  • 200ug
  • 1mg
产品介绍
Catalog NumberMOP2297
Alias金属基质金属蛋白酶抑制因子1, EPA, Clgi, Timp, TIMP 1, TPA S1, tissue inhibitor of metalloproteinase 1
Size20ug, 50ug, 100ug, 200ug, 1mg
Product DescriptionMOP2297 Recombinant Mouse Timp-1 Protein, C-His tag contains the mouse Timp1(Cys25-Arg205) was expressed in Mammalian cells.
Molecular NameTimp1
Product IntroductionTimp1 (MOP2297) 是一种金属蛋白酶抑制剂,参与调节细胞外基质的降解。
Molecular Weight32 kDa
Expression SystemHEK293F Cells
SpeciesMouse
Concentration联系销售经理获得最新批次的浓度
Purity≥95%
SDS-PAGE
PurificationAffinity Purification
Uniprot IDP12032
Storage ConditionStore the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles.
FormulationPBS
Shipping ConditionThis product is shipped on ice packs or dry ice.
BackgroundThe tissue inhibitor of metalloproteinases (TIMP-1) is a glycoprotein with a molecular mass of about 28-kDa. The secreted protein consists of 184 amino acids, six disuilfide bonds and two glycosylation sites containing N-linked oligosaccharides. TIMP-1 specifically inhibits the extracellular-matrix-degrading metalloproteinases such as collagenase, gelatinase and stromelysin. It has no activity on mammalian membrane metallo-proteinases, procollagen peptidase, or on bacterial metalloproteinases such as thermolysin.
Endotoxin< 0.1 EU per ug
Protein FamilyOther protein
Biological ActivityMeasured by its ability to inhibit human MMP-2 cleavage of a fluorogenic peptide substrate McaPLGL-Dpa-ARNH2. The IC50 value is <3.5 nM, as measured underthe described conditions.
Product Declaration该产品仅供科研使用,不可直接用于人体或注射。

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