Recombinant Mouse OX40/Tnfsf4 Protein, C-hFc and His tag
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产品编号
MOP2234
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别名
肿瘤坏死因子受体超家族成员4, Ox40, ACT35, CD134, Ly 70, Txgp1, TXGP1L, tumor necrosis factor receptor superfamily, member 4
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规格
- 20ug
- 50ug
- 100ug
- 200ug
- 1mg
产品介绍
| Catalog Number | MOP2234 |
| Alias | 肿瘤坏死因子受体超家族成员4, Ox40, ACT35, CD134, Ly 70, Txgp1, TXGP1L, tumor necrosis factor receptor superfamily, member 4 |
| Size | 20ug, 50ug, 100ug, 200ug, 1mg |
| Product Description | MOP2234 Recombinant Mouse OX40/Tnfsf4 Protein, C-hFc and His tag contains the mouse Tnfrsf4(Val20-Pro211) was expressed in Mammalian cells. |
| Molecular Name | Tnfrsf4 |
| Product Introduction | (MOP2234) TNFSF4是肿瘤坏死因子超家族成员，调节T细胞活化和免疫反应。 |
| Molecular Weight | 65-75 kDa |
| Expression System | HEK293F Cells |
| Species | Mouse |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purity | ≥95% |
| SDS-PAGE | |
| Purification | Affinity Purification |
| Uniprot ID | P47741 |
| Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. |
| Formulation | PBS |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Background | OX4L, a member of the TNF superfamily of structurally related proteins, exists primarily as a type II membrane bound, non-covalently linked homotrimeric protein. It is expressed on antigen presenting cells (APCs), such as dendritic cells and activated B-cells, and also on various other cells such as vascular endothelial cells, mast cells, and natural killer cells. OX4L signals specifically through the OX4 receptor, which is expressed predominantly on CD4+T cells but also on certain activated CD8+T cells. OX4/OX4L functions as a costimulatory signal, which is required for a productive interaction between antigen presenting cells and their target T-cells. |
| Endotoxin | < 0.1 EU per ug |
| Protein Family | Other protein |
| Biological Activity | Measured by its ability to inhibit OX40 Ligand induced IL-2 secretion by mouse T cells. The ED50 for this effect is 0.1-0.3 µg/mL in the presence of 30 ng/mL of Recombinant Mouse OX40 Ligand/TNFSF4. |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
FAQ
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如何确保蛋白表达的质量？
通过优化表达条件、使用高质量的培养基和转染试剂，并通过纯化后检测蛋白的活性和纯度来确保蛋白质量。
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