Recombinant Mouse Mmp12 Protein, His Tag
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产品编号
MOP2227
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别名
MME, Mmel, AV378681, matrix metallopeptidase 12
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规格
- 50ug
- 100ug
Alias | MME, Mmel, AV378681, matrix metallopeptidase 12 |
Catalog Number | MOP2227 |
Molecular Name | Mmp12 |
Species | Mouse |
Host | Mammalian cells |
Size | 50ug, 100ug |
Protein Family | Other protein |
Purity | ≥90% as determined by SDS-PAGE |
Purification | Affinity Purification |
Endotoxin | < 1.0 EU per ug of the protein as determined by the LAL method. |
Formulation | PBS |
Background | Macrophage metalloelastase is an enzyme that in humans is encoded by the MMP12 gene. Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP"s are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. It is thought that the protein encoded by this gene is cleaved at both ends to yield the active enzyme, but this processing has not been fully described. The enzyme degrades soluble and insoluble elastin. It may play a role in aneurysm formation and studies in mice suggest a role in the development of emphysema. |
Storage Condition | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |
Shipping Condition | This product is shipped on ice packs or dry ice. |
Molecular Weight | 48.95 kDa |
Note | 仅供科研使用 |