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Recombinant Mouse Light/Tnfsf14/CD258 Protein, N-His

Recombinant Mouse Light/Tnfsf14/CD258 Protein, N-His

产品编号

MOP2218

别名

肿瘤坏死因子超家族成员14, LTg, HVEML, LIGHT, Ly113, HVEM L, Tnlg1d, tumor necrosis factor(ligand) superfamily, member 14

规格
  • 20ug
  • 50ug
  • 100ug
  • 200ug
  • 1mg
产品介绍
Catalog NumberMOP2218
Alias肿瘤坏死因子超家族成员14, LTg, HVEML, LIGHT, Ly113, HVEM L, Tnlg1d, tumor necrosis factor(ligand) superfamily, member 14
Size20ug, 50ug, 100ug, 200ug, 1mg
Product DescriptionMOP2218 Recombinant Mouse Light/Tnfsf14/CD258 Protein, N-His contains the mouse Tnfsf14(72-239 aa) was expressed in Mammalian cells.
Molecular NameTnfsf14
Product IntroductionTnfsf14是肿瘤坏死因子超家族成员,调节免疫细胞的活性和增殖。
Molecular Weight24 kDa
Expression SystemHEK293F Cells
SpeciesMouse
Concentration联系销售经理获得最新批次的浓度
Purity≥95%
PurificationAffinity Purification
Uniprot IDQ9QYH9
Storage ConditionStore the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles.
FormulationPBS
Shipping ConditionThis product is shipped on ice packs or dry ice.
BackgroundLIGHT is a type II transmemebrane protein and a member of the TNF cytokine family also referred to as TNFSF14 and it is identical with HVEM ligand. LIGHT is expressed in splenocytes, activated PBL, CD8+ tumor infiltrating lymphocytes, granulocytes and monocytes. LIGHT has the ability to activate NFkB, stimulate proliferation of lymphocytes, and induce apoptosis in certain human tumor cells. LIGHT binds to three receptors; the herpes virus entry mediator type A receptor (HEVM), LTbR and a decoy receptor (DcR3).
Endotoxin< 0.1 EU per ug
Protein FamilyOther protein
Biological ActivityMeasured in a cytotoxicity assay using HT‑29 human colon adenocarcinoma cells. The ED50 forthis effect isforthis effect is less than 5 µg/mL in the presence of a cross-linking antibody, Mouse Anti-polyHistidine Monoclonal Antibody and recombinant human IF
Product Declaration该产品仅供科研使用,不可直接用于人体或注射。

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