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Recombinant Mouse Il-13/Il13 Protein, C-His tag

Recombinant Mouse Il-13/Il13 Protein, C-His tag

产品编号

MOP2198

别名

白细胞介素13, Il 13, interleukin 13

规格
  • 20ug
  • 50ug
  • 100ug
  • 200ug
  • 1mg
产品介绍
Catalog NumberMOP2198
Alias白细胞介素13, Il 13, interleukin 13
Size20ug, 50ug, 100ug, 200ug, 1mg
Product DescriptionMOP2198 Recombinant Mouse Il-13/Il13 Protein, C-His tag contains the mouse Il13(26-131 aa) was expressed in Mammalian cells.
Molecular NameIl13
Product IntroductionIl13 (MOP2198) 调节免疫反应,主要在过敏性反应和免疫耐受性中起作用。
Molecular Weight15-30 kDa
Expression SystemHEK293F Cells
SpeciesMouse
Concentration联系销售经理获得最新批次的浓度
Purity≥95%
PurificationAffinity Purification
Uniprot IDP20109
Storage ConditionStore the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles.
FormulationPBS
Shipping ConditionThis product is shipped on ice packs or dry ice.
BackgroundInterleukin 13 (IL-13) is a single-chain cytokine which belongs to the IL13/IL4 family. In humans, IL13 is secreted by many cell types, but especially by T helper type 2 (Th2) cells. IL13 inhibits the production of pro-inflammatory cytokines and chemokines, and thus down-regulates macrophage activity. Meanwhile, IL-13 synergizes with IL2 in regulating IFN-gamma synthesis. IL-13 binds to a multi-subunit receptor comprising the alpha chain of the IL-4 receptor (IL-4Rα) and at least one of two known IL-13-specific binding chains (IL13 Rα1 and IL13 Rα2), and exerts its effects through signal transducer and activator of transcription 6 (STAT6), like IL-4. Accordingly, IL-13 may be critical in regulating inflammatory and immune responses as a central mediator in various cell types.
Endotoxin< 0.1 EU per ug
Protein FamilyOther protein
Biological ActivityMeasured in a cell proliferation assay using TF-1 Mouse erythroleukemic cells. The ED50 forthis effect is 23.9-95.6 ng/mL, corresponding to a specific activity of 1.05×10^4- 4.18×10^4 units/mg.
Product Declaration该产品仅供科研使用,不可直接用于人体或注射。

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