Recombinant Mouse Il-13/Il13 Protein, C-His tag
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产品编号
MOP2198
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别名
白细胞介素13, Il 13, interleukin 13
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规格
- 20ug
 - 50ug
 - 100ug
 - 200ug
 - 1mg
 
 
| Catalog Number | MOP2198 | 
| Alias | 白细胞介素13, Il 13, interleukin 13 | 
| Size | 20ug, 50ug, 100ug, 200ug, 1mg | 
| Product Description | MOP2198 Recombinant Mouse Il-13/Il13 Protein, C-His tag contains the mouse Il13(26-131 aa) was expressed in Mammalian cells. | 
| Molecular Name | Il13 | 
| Product Introduction | Il13 (MOP2198) 调节免疫反应,主要在过敏性反应和免疫耐受性中起作用。 | 
| Molecular Weight | 15-30 kDa | 
| Expression System | HEK293F Cells | 
| Species | Mouse | 
| Concentration | 联系销售经理获得最新批次的浓度 | 
| Purity | ≥95% | 
| Purification | Affinity Purification | 
| Uniprot ID | P20109 | 
| Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. | 
| Formulation | PBS | 
| Shipping Condition | This product is shipped on ice packs or dry ice. | 
| Background | Interleukin 13 (IL-13) is a single-chain cytokine which belongs to the IL13/IL4 family. In humans, IL13 is secreted by many cell types, but especially by T helper type 2 (Th2) cells. IL13 inhibits the production of pro-inflammatory cytokines and chemokines, and thus down-regulates macrophage activity. Meanwhile, IL-13 synergizes with IL2 in regulating IFN-gamma synthesis. IL-13 binds to a multi-subunit receptor comprising the alpha chain of the IL-4 receptor (IL-4Rα) and at least one of two known IL-13-specific binding chains (IL13 Rα1 and IL13 Rα2), and exerts its effects through signal transducer and activator of transcription 6 (STAT6), like IL-4. Accordingly, IL-13 may be critical in regulating inflammatory and immune responses as a central mediator in various cell types. | 
| Endotoxin | < 0.1 EU per ug | 
| Protein Family | Other protein | 
| Biological Activity | Measured in a cell proliferation assay using TF-1 Mouse erythroleukemic cells. The ED50 forthis effect is 23.9-95.6 ng/mL, corresponding to a specific activity of 1.05×10^4- 4.18×10^4 units/mg. | 
| Product Declaration | 该产品仅供科研使用,不可直接用于人体或注射。 | 
							
							
							
							
						
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