| Catalog Number | MOP2145 |
| Alias | Fas/Tnfrsf6/CD95, lpr, APO1, APT1, CD95, TNFR6, Tnfrsf6, AI196731, Fas(TNF receptor superfamily member 6) |
| Size | 20ug, 50ug, 100ug, 200ug, 1mg |
| Product Description | MOP2145 Recombinant Mouse Fas/Tnfrsf6/Cd95 C-FC Protein, C-hFc and His tag contains the mouse Fas(14-169 aa) was expressed in Mammalian cells. |
| Molecular Name | Fas |
| Product Introduction | Fas/Tnfrsf6/Cd95 (MOP2145) Fas/Tnfrsf6/CD95是一种受体，参与调节细胞凋亡、免疫反应及自我容忍。 |
| Molecular Weight | 55 kDa |
| Expression System | HEK293F Cells |
| Species | Mouse |
| Concentration | 联系销售经理获得最新批次的浓度 |
| Purity | ≥95% |
| SDS-PAGE |  |
| Purification | Affinity Purification |
| Uniprot ID | P25446 |
| Storage Condition | Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles. |
| Formulation | PBS |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Background | Apo-1 (Fas/CD95) is a 45 kD type I transmembrane protein belonging to the TNF receptor family. A subgroup of this receptor family called death receptors contain 3-4 cysteine-rich repeats in the extracellular portion and a cystoplasmic motif called the death domain, which is responsible for the transduction of the death signal. The death domain associates with FADD/MORT, which in turn connects to aspartate-specific proteases (Caspases) that are implicated as mediators of most types of apoptotic cell death (6-9). |
| Endotoxin | < 0.1 EU per ug |
| Protein Family | Other protein |
| Biological Activity | Measured by its ability to inhibit Fas Ligand-induced apoptosis of Jurkat human acute T cell leukemia cells. The ED50 forthis effect is 0.03‑0.1 µg/mL in the presence of 20 ng/mL recombinant human Fas-ligand. |
| Product Declaration | 该产品仅供科研使用，不可直接用于人体或注射。 |
通过优化表达条件、使用高质量的培养基和转染试剂，并通过纯化后检测蛋白的活性和纯度来确保蛋白质量。
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