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Recombinant Mouse Complement C5 Protein, No tag

Recombinant Mouse Complement C5 Protein, No tag

产品编号

MOP2106

别名

补体C5, C5, He, C5a, Hfib2, hemolytic complement

规格
  • 20ug
  • 50ug
  • 100ug
  • 200ug
  • 1mg
产品介绍
Catalog NumberMOP2106
Alias补体C5, C5, He, C5a, Hfib2, hemolytic complement
Size20ug, 50ug, 100ug, 200ug, 1mg
Product DescriptionMOP2106 Recombinant Mouse Complement C5 Protein, No tag contains the mouse C5(Asn679-Arg755) was expressed in E. coli.
Molecular NameHc
Product IntroductionHc (MOP2106) 是补体系统中的一个关键成分,调节免疫反应及炎症反应。
Molecular Weight9 kDa
Expression SystemE. coli
SpeciesMouse
Concentration联系销售经理获得最新批次的浓度
Purity≥95%
PurificationAffinity Purification
Uniprot IDP06684
Storage ConditionStore the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles.
FormulationPBS
Shipping ConditionThis product is shipped on ice packs or dry ice.
BackgroundMouse Hc is a 77-amino acid peptide generated during complement activation from the α-chain of complement C5. Mouse Hc shares 6% and 82% amino acid sequence identity to human and rat Hc, respectively. Hc binds to a signaling G-protein coupled receptor (GPCR) (C5aR/CD88), inducing neutrophil chemotaxis and endothelial cell activation. It also triggers an oxidative burst in macrophages and neutrophils, and induces release of histamine in basophils and mast cells.
Endotoxin< 0.1 EU per ug
Protein FamilyOther protein
Biological ActivityMeasured by its ability to induce N-acetyl-beta -D-glucosaminidase release from differentiated U937 human histiocytic lymphoma cells. The ED50 for this effect is 5-20 ng/mL.
Product Declaration该产品仅供科研使用,不可直接用于人体或注射。

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