| Alias | Bl2, ST17, Igsf4, Necl2, RA175, Tslc1, Igsf4a, RA175A, RA175B, RA175C, RA175N, SgIGSF, SynCam, AI987920, 2900073G06Rik, 3100001I08Rik, cell adhesion molecule 1 |
| Catalog Number | MOP2084 |
| Molecular Name | Cadm1 |
| Species | Mouse |
| Host | Mammalian cells |
| Size | 50ug, 100ug |
| Protein Family | Other protein |
| Purity | ≥90% as determined by SDS-PAGE |
| Purification | Affinity Purification |
| Endotoxin | < 1.0 EU per ug of the protein as determined by the LAL method. |
| Formulation | PBS |
| Background | Cadm1 is a 75 kDaimmunoglobulin superfamily protein that mediates calcium-independent adhesiveinteractions, either homophilic or heterophilic with CRTAM (classI-restricted T cell-associated molecule), Necl1 (SynCAM3) or Nectin3.Alternate names for Cadm1 reflect its activities. As Cadm1, it isdownregulated in onsmall cell lung cancer. This may allow evasion ofantitumor responses, since Cadm1 interaction with CRTAM on activated NK andCD8+ T cells stimulates cytotoxicity and upregulates IFN-γ production. |
| Storage Condition | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Molecular Weight | 62.51 kDa |
| Note | 仅供科研使用 |
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